| Sequence 1: | NP_525099.3 | Gene: | Hrs / 33458 | FlyBaseID: | FBgn0031450 | Length: | 760 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_067083.1 | Gene: | ZFYVE1 / 53349 | HGNCID: | 13180 | Length: | 777 | Species: | Homo sapiens |
| Alignment Length: | 291 | Identity: | 64/291 - (21%) |
|---|---|---|---|
| Similarity: | 97/291 - (33%) | Gaps: | 85/291 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3 RSSFDKNLENATSHLRLEPDWPSILLIC--------------DEINQKDVTPKNAF--------- 44
Fly 45 -AAIKKKMNSPN---PH-------------------SSCYSLLVLESIVKNCGAPVHEE------ 80
Fly 81 ------VFTKENC-EMFSS----FLESTPHENVRQKMLELVQTW----AYAFRSSDKYQAIKDTM 130
Fly 131 TILKAKGHTFPEL-----READAMFTADTAP-NWADGR---VCHRCRVEFTFTNRKHHCRNCGQV 186
Fly 187 FCGQCTAKQCPLPKYGI-EKEVRVCDGCFAA 216 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Hrs | NP_525099.3 | VHS_Hrs_Vps27p | 2..143 | CDD:239626 | 34/206 (17%) |
| FYVE_Hrs | 157..217 | CDD:277260 | 25/64 (39%) | ||
| Hrs_helical | 377..471 | CDD:289018 | |||
| GBP_C | <456..520 | CDD:303769 | |||
| coiled coil | 501..512 | CDD:293879 | |||
| ZFYVE1 | NP_067083.1 | GBP | 174..410 | CDD:206650 | 7/37 (19%) |
| Required for localization in the lipid droplets. /evidence=ECO:0000269|PubMed:30970241, ECO:0000269|PubMed:31293035 | 416..777 | 56/247 (23%) | |||
| FYVE_like_SF | 594..655 | CDD:333710 | 23/60 (38%) | ||
| FYVE_ZFYV1 | 711..771 | CDD:277273 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1818 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||