DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and CYC8

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_009670.3 Gene:CYC8 / 852410 SGDID:S000000316 Length:966 Species:Saccharomyces cerevisiae


Alignment Length:551 Identity:115/551 - (20%)
Similarity:187/551 - (33%) Gaps:131/551 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   198 LCKETAITALLLCGLCDVLSPVGRENSDKVCDGSISGLASFNFQRRFRSLSILGFTLLCGLYCRL 262
            |.:.||.|.|.:..|.:.|.           ||..:.:| ::...:|...|....|.|..||...
Yeast    41 LTQSTAETWLSIASLAETLG-----------DGDRAAMA-YDATLQFNPSSAKALTSLAHLYRSR 93

  Fly   263 SLLPRPSTAFSAADNPTAHESCFWTRTLTFLYLPVANFGILLWPQELSFDWGM--EAVSRIRTLW 325
            .:..|.:..:..|                           ||...|||..|..  .....:..|.
Yeast    94 DMFQRAAELYERA---------------------------LLVNPELSDVWATLGHCYLMLDDLQ 131

  Fly   326 DARNILTAGFY---GSLVAILWKGSG-LRSAASPMDFAEVANISLPLLRRLGGNSCHTWLGLTCD 386
            .|.|......|   ...|..||.|.| |......:|:||.|...:                |..|
Yeast   132 RAYNAYQQALYHLSNPNVPKLWHGIGILYDRYGSLDYAEEAFAKV----------------LELD 180

  Fly   387 CHHQLSAPSYRSASAIYSTSSKSKSASWTAAPILGTAFLVLPFLPAS----NLLFYVGFVMAERV 447
            .|.:.:...|.....||....|     |:.|  |.....:||..||.    ::.|.:|.|     
Yeast   181 PHFEKANEIYFRLGIIYKHQGK-----WSQA--LECFRYILPQPPAPLQEWDIWFQLGSV----- 233

  Fly   448 LYLPSVGYCLLFGLGFGHLWQRVNSSWRSRL-------MLLCGLALLLGVHGVRTF--RRNLDWR 503
              |.|:|.           ||....::...|       .:|..|..|.|:..|:.:  ::.||: 
Yeast   234 --LESMGE-----------WQGAKEAYEHVLAQNQHHAKVLQQLGCLYGMSNVQFYDPQKALDY- 284

  Fly   504 DEEQLFRSAISINPPKALG--NLGSVLSAQGRYEEAELTLRMTLGHRPTMADAHFNLGVVHQKQL 566
                |.:| :..:|..|..  :||.|...:..|..|....:..:...........::||::.:..
Yeast   285 ----LLKS-LEADPSDATTWYHLGRVHMIRTDYTAAYDAFQQAVNRDSRNPIFWCSIGVLYYQIS 344

  Fly   567 NFSSAIPCFRRAIELRPQLAVAYLNLGTSLISLGDHRQEAISVLRTGARLEGSGVRDRGAHVEAR 631
            .:..|:..:.|||.|.|.::..:.:|||...:..:...:|:...:..|||:.:.|     |:..|
Yeast   345 QYRDALDAYTRAIRLNPYISEVWYDLGTLYETCNNQLSDALDAYKQAARLDVNNV-----HIRER 404

  Fly   632 YTCYLQLSVLYRSDGRLQDAAAALRESLKALP-------LLPQKQRAVLHLRLGEILAELQDWNE 689
            ...   |:....:.|.:..:..|...:..|.|       |.|..|...|:.|   |.|:..:...
Yeast   405 LEA---LTKQLENPGNINKSNGAPTNASPAPPPVILQPTLQPNDQGNPLNTR---ISAQSANATA 463

  Fly   690 AEHQQRLAMQLQPEQGAAYVTYGQTLARNGS 720
            :..||:...|..|...:|      |:..||:
Yeast   464 SMVQQQHPAQQTPINSSA------TMYSNGA 488

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594 11/72 (15%)
TPR_11 518..583 CDD:290150 13/66 (20%)
TPR repeat 518..546 CDD:276809 6/29 (21%)
TPR repeat 551..581 CDD:276809 6/29 (21%)
TPR_1 552..584 CDD:278916 7/31 (23%)
TPR 565..841 CDD:223533 36/163 (22%)
TPR repeat 586..611 CDD:276809 4/24 (17%)
TPR repeat 634..660 CDD:276809 3/25 (12%)
TPR repeat 671..699 CDD:276809 6/27 (22%)
TPR repeat 704..735 CDD:276809 4/17 (24%)
TPR repeat 740..768 CDD:276809
TPR repeat 773..803 CDD:276809
TPR 808..841 CDD:197478
TPR repeat 808..836 CDD:276809
CYC8NP_009670.3 TPR <38..142 CDD:223533 27/139 (19%)
TPR repeat 46..74 CDD:276809 8/39 (21%)
TPR repeat 80..108 CDD:276809 6/54 (11%)
TPR 94..391 CDD:223533 73/370 (20%)
TPR repeat 113..143 CDD:276809 6/29 (21%)
TPR repeat 150..178 CDD:276809 9/43 (21%)
TPR repeat 184..211 CDD:276809 7/33 (21%)
TPR repeat 223..253 CDD:276809 9/47 (19%)
TPR repeat 258..290 CDD:276809 9/37 (24%)
TPR repeat 296..324 CDD:276809 6/27 (22%)
TPR repeat 329..359 CDD:276809 6/29 (21%)
TPR repeat 364..393 CDD:276809 4/28 (14%)
Herpes_BLLF1 <697..944 CDD:282904
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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