DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31690 and ifit14

DIOPT Version :9

Sequence 1:	NP_995615.2	Gene:	CG31690 / 33455	FlyBaseID:	FBgn0051690	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001287802.1	Gene:	ifit14 / 794786	ZFINID:	ZDB-GENE-131120-20	Length:	433	Species:	Danio rerio

Alignment Length:	285	Identity:	66/285 - (23%)
Similarity:	105/285 - (36%)	Gaps:	86/285 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   599 LGDHRQEAISVLRTGARLEGSGVRDRGAHVEARYTC-----YLQLSVLYRSDG-------RLQDA 651
            ||.::.|.            .|::.:..||:.:...     |..|..:.:|.|       .||.|
Zfish    20 LGQYQNEL------------QGMKRKMDHVDPQKISSPVHYYNLLGFIQKSLGSDREALESLQKA 72

  Fly   652 AAALRE---SLKALPLLPQKQR-AVLHLRLGEILAELQDWNEAEHQQRL-----AMQLQPEQGAA 707
            .:.::|   ...|:.||..|.. |.::..|||:........|.|..||:     ...|.||...
Zfish    73 ESVIQEQGTEETAVRLLVNKANLAWVYFYLGELEKSRGYLEELEELQRIHPAPPGCPLHPEVSG- 136

  Fly   708 YVTYGQTLAR-NGSRLAEAESWFKRALQLAPLEPSSHHHYADFLEQQERHHEALGLRLRAAALAP 771
              ..|.||.: |.|:.::|..:||.||:..|             |::|.|.   ||.:
Zfish   137 --EKGWTLVKFNKSKKSQAIGYFKMALEAEP-------------ERKEWHK---GLAI------- 176

  Fly   772 QDYTLQSCVADALRLLNRLAEAELWYR-----KAVTLQPM--AAHAHANLGAILQMRGLRKEAVA 829
                             .:::|.|||:     ||..|:.:  ||....|...:..:..|:|..|.
Zfish   177 -----------------SMSKACLWYKCTPEQKAEILEKVKTAAEIDPNDLFLQSLYVLKKFEVQ 224

  Fly   830 CYHKALELQP--GHAISRANLARMN 852
            ..:...|:|.  ..:||.|||..:|
Zfish   225 GENVDEEIQSLLKKSISTANLVGLN 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31690	NP_995615.2	DUF1736	272..340	CDD:285594
		TPR_11	518..583	CDD:290150
		TPR repeat	518..546	CDD:276809
		TPR repeat	551..581	CDD:276809
		TPR_1	552..584	CDD:278916
		TPR	565..841	CDD:223533	60/272 (22%)
		TPR repeat	586..611	CDD:276809	3/11 (27%)
		TPR repeat	634..660	CDD:276809	8/40 (20%)
		TPR repeat	671..699	CDD:276809	8/32 (25%)
		TPR repeat	704..735	CDD:276809	10/31 (32%)
		TPR repeat	740..768	CDD:276809	5/27 (19%)
		TPR repeat	773..803	CDD:276809	6/34 (18%)
		TPR	808..841	CDD:197478	7/34 (21%)
		TPR repeat	808..836	CDD:276809	5/27 (19%)
ifit14	NP_001287802.1	TPR_12	47..120	CDD:290160	18/72 (25%)
		TPR repeat	248..272	CDD:276809	1/2 (50%)
		TPR repeat	277..319	CDD:276809
		TPR repeat	324..352	CDD:276809
		TPR repeat	358..392	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810