DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31690 and Odad4

DIOPT Version :9

Sequence 1:	NP_995615.2	Gene:	CG31690 / 33455	FlyBaseID:	FBgn0051690	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_083194.2	Gene:	Odad4 / 74407	MGIID:	1921657	Length:	624	Species:	Mus musculus

Alignment Length:	228	Identity:	50/228 - (21%)
Similarity:	86/228 - (37%)	Gaps:	54/228 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   644 SDGRLQDAAAALRESLK-ALPLLPQKQRAV---------LHLRLGEILAELQDWNEAEHQQRLAM 698
            :||.||.|...|::.|: ....:|.|...|         ..:.||:::|.||     .|::.|.:
Mouse   288 ADGSLQKAEKVLKKVLEWNQEEVPNKDELVGNLYSCIGNAQIELGQMVAALQ-----SHRKDLEI 347

  Fly   699 ----QLQPEQGAAYVTYGQTLARNGSRLAEAESWFKR-ALQLAPLEPSSHHH------------- 745
                .|...:..|....|:..||.|......::|.:: .|....||.:...|
Mouse   348 AKEHDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAW 412

  Fly   746 ----YADFLEQQERHHEALGLRLRAAALAPQ------DYTLQSCVADALRLLNRLAEAELWYRKA 800
                |.:..:|.......|..:|.|:.|..|      |:  :|.|.:..:.|.|   |:|.:...
Mouse   413 QAQSYGEKSQQYAEEEGDLEWQLNASVLVAQAQVKLRDF--ESAVNNFEKALER---AKLVHNNE 472

  Fly   801 VTLQPMAAHAHANLGAILQMRG------LRKEA 827
            .....::|...||.|.|.:::.      ||::|
Mouse   473 AQQAIISALDDANKGIIEELKKTNYREILREKA 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31690	NP_995615.2	DUF1736	272..340	CDD:285594
		TPR_11	518..583	CDD:290150
		TPR repeat	518..546	CDD:276809
		TPR repeat	551..581	CDD:276809
		TPR_1	552..584	CDD:278916
		TPR	565..841	CDD:223533	50/228 (22%)
		TPR repeat	586..611	CDD:276809
		TPR repeat	634..660	CDD:276809	6/15 (40%)
		TPR repeat	671..699	CDD:276809	8/40 (20%)
		TPR repeat	704..735	CDD:276809	7/31 (23%)
		TPR repeat	740..768	CDD:276809	6/44 (14%)
		TPR repeat	773..803	CDD:276809	7/29 (24%)
		TPR	808..841	CDD:197478	8/26 (31%)
		TPR repeat	808..836	CDD:276809	8/26 (31%)
Odad4	NP_083194.2	TPR 1. /evidence=ECO:0000255	11..44
		TPR_11	14..76	CDD:290150
		TPR repeat	14..39	CDD:276809
		TPR repeat	44..74	CDD:276809
		TPR 2. /evidence=ECO:0000255	46..78
		TPR_11	47..110	CDD:290150
		TPR 3. /evidence=ECO:0000255	79..112
		TPR repeat	79..107	CDD:276809
		TPR 4. /evidence=ECO:0000255	273..309		7/20 (35%)
		TPR repeat	309..347	CDD:276809	10/42 (24%)
		TPR_12	314..383	CDD:290160	15/73 (21%)
		TPR 5. /evidence=ECO:0000255	318..351		7/37 (19%)
		TPR 6. /evidence=ECO:0000255	358..391		7/32 (22%)
		TPR repeat	358..383	CDD:276809	6/24 (25%)
		TPR_12	359..427	CDD:290160	12/67 (18%)
		TPR 7. /evidence=ECO:0000255	395..428		3/32 (9%)
		TPR_12	396..466	CDD:290160	13/74 (18%)
		TPR repeat	429..463	CDD:276809	8/35 (23%)
		TPR 8. /evidence=ECO:0000255	435..468		10/37 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	511..624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900