DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and Dnaaf4

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_080590.3 Gene:Dnaaf4 / 67685 MGIID:1914935 Length:420 Species:Mus musculus


Alignment Length:270 Identity:59/270 - (21%)
Similarity:96/270 - (35%) Gaps:90/270 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   649 QDAAAALRESLKALPLLPQKQRAVLHLRLGE---ILAELQDWNE----AEHQQRLAMQLQPEQG- 705
            :|...||.|.:|   :..::::.:..::..|   ..:||:.|.|    |:.|:|:..:.:|.:| 
Mouse   124 EDQRYALGEMMK---IEEEERKKIEDMKENERKKATSELEAWKECQKKADGQKRVQRKEKPLEGK 185

  Fly   706 ---------------AAYVTYGQTLARN------------------------------------- 718
                           .|..|...|..||                                     
Mouse   186 QAEETKALKPRGLPRKAPPTRLPTRGRNWENIFPEKLKEDRVPAPRSAGSIQISFTPRVFPTALR 250

  Fly   719 GSRLAEAESWFKRALQLAPLEPSSHHHYADFLEQQERHHEAL---GLRLRAAALAPQDYTLQSCV 780
            .|::||.|.|..:..:......:....:.| |:::||:.:.|   |.:|    .|.::|.   ..
Mouse   251 ESQVAEEEEWLHKQAEARRAMSTDLPEFFD-LKEEERNPDWLKDKGNKL----FATENYL---AA 307

  Fly   781 ADALRLLNRL-AEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALELQPGHAIS 844
            .||..|..|| .:..|.|     |...|.|        |:::.|.| |:....|||||.......
Mouse   308 VDAYNLAIRLNCKIPLLY-----LNRAACH--------LKLKNLHK-AIEDSSKALELLTPPVAD 358

  Fly   845 RANLARMNVH 854
            .|| |||..|
Mouse   359 NAN-ARMKAH 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150
TPR repeat 518..546 CDD:276809
TPR repeat 551..581 CDD:276809
TPR_1 552..584 CDD:278916
TPR 565..841 CDD:223533 53/255 (21%)
TPR repeat 586..611 CDD:276809
TPR repeat 634..660 CDD:276809 4/10 (40%)
TPR repeat 671..699 CDD:276809 8/34 (24%)
TPR repeat 704..735 CDD:276809 11/83 (13%)
TPR repeat 740..768 CDD:276809 7/30 (23%)
TPR repeat 773..803 CDD:276809 8/30 (27%)
TPR 808..841 CDD:197478 10/32 (31%)
TPR repeat 808..836 CDD:276809 7/27 (26%)
Dnaaf4NP_080590.3 Mediates interaction with ESR1 and STUB1. /evidence=ECO:0000250 7..103
p23_DYX1C1_like 10..87 CDD:107226
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 164..212 9/47 (19%)
TPR_11 287..351 CDD:290150 22/84 (26%)
TPR 1 288..321 10/39 (26%)
TPR repeat 288..316 CDD:276809 8/34 (24%)
TPR repeat 321..351 CDD:276809 12/43 (28%)
TPR 2 322..355 14/46 (30%)
TPR_1 322..351 CDD:278916 12/42 (29%)
TPR_12 324..396 CDD:290160 19/59 (32%)
TPR repeat 362..392 CDD:276809 4/6 (67%)
TPR 3 364..397 2/4 (50%)
TPR_1 365..397 CDD:278916 1/3 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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