DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31690 and Ifit3b

DIOPT Version :9

Sequence 1:	NP_995615.2	Gene:	CG31690 / 33455	FlyBaseID:	FBgn0051690	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	XP_006527327.1	Gene:	Ifit3b / 667370	MGIID:	3698419	Length:	428	Species:	Mus musculus

Alignment Length:	295	Identity:	67/295 - (22%)
Similarity:	108/295 - (36%)	Gaps:	70/295 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   507 QLFRSAISINPPKALGNLGSVLSAQGRYEEAELTLRMTLGHRPT-------MADAHFNLGVVHQK 564
            |.|.:..|:..|:.....|......||.|.|::.....|..:|.       ||.|.|.|....:|
Mouse   150 QKFANPYSMECPELECEEGWTRLKCGRNERAKMCFEKALEEKPKDPECSSGMAIAMFRLEEKPEK 214

  Fly   565 QLNFSSAIPCFRRAIELRPQLAVAYLNLGTSLISLGDHRQEAISVLRTGARLEGSGVRDRGAHVE 629
            |.    ::...::|:||.||.....:.|...|:.:|:..:        |.||    ::|......
Mouse   215 QF----SVDALKQAMELNPQNQYVKVLLALKLLRMGEEAE--------GERL----IKDALGKAP 263

  Fly   630 ARYTCYLQLSVLYRSDGRLQDA----AAALRESLKALPLLPQKQRAVLHLRLGEILAELQ---DW 687
            .:.....:.:..|:..|.|..|    ..|||.::...||.     :::..|..|||.:||   |.
Mouse   264 NQTDVLQKAAQFYKKKGNLDRAIELLGKALRSTVNNSPLY-----SLVMCRYREILEQLQNKGDA 323

  Fly   688 NEAEHQQRLA---------MQLQPEQGAAYVTYGQTLARNGSRL---------AEAESWFKRALQ 734
            :.:|.:||:|         ||             :||.|..|.|         .|.|..::..:.
Mouse   324 DSSERRQRMAELRRLTMEFMQ-------------KTLQRRRSPLNSYSDLIDFPEVERCYQMVIS 375

  Fly   735 LAPLEPSSHHHYADFLEQQERHHEALGLRLRAAAL 769
            ....:......|..:...||.|.::..|    |||
Mouse   376 KESPDVEEEDLYERYCNLQEYHRKSEDL----AAL 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31690	NP_995615.2	DUF1736	272..340	CDD:285594
		TPR_11	518..583	CDD:290150	18/71 (25%)
		TPR repeat	518..546	CDD:276809	6/27 (22%)
		TPR repeat	551..581	CDD:276809	8/29 (28%)
		TPR_1	552..584	CDD:278916	9/31 (29%)
		TPR	565..841	CDD:223533	50/230 (22%)
		TPR repeat	586..611	CDD:276809	3/24 (13%)
		TPR repeat	634..660	CDD:276809	7/29 (24%)
		TPR repeat	671..699	CDD:276809	11/39 (28%)
		TPR repeat	704..735	CDD:276809	7/39 (18%)
		TPR repeat	740..768	CDD:276809	5/27 (19%)
		TPR repeat	773..803	CDD:276809
		TPR	808..841	CDD:197478
		TPR repeat	808..836	CDD:276809
Ifit3b	XP_006527327.1	TPR repeat	76..104	CDD:276809
		PEP_TPR_lipo	<81..>325	CDD:274350	46/195 (24%)
		TPR repeat	109..148	CDD:276809
		TPR repeat	161..189	CDD:276809	6/27 (22%)
		TPR repeat	194..227	CDD:276809	8/36 (22%)
		TPR repeat	266..294	CDD:276809	5/27 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810