DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and Ifit1

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_064481.1 Gene:Ifit1 / 56824 RGDID:620599 Length:463 Species:Rattus norvegicus


Alignment Length:446 Identity:99/446 - (22%)
Similarity:162/446 - (36%) Gaps:138/446 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   488 LGVHGVRTFRRNLDWRDEEQLFRSAISINPPKALGNLGSVLSAQGRYEEAELTLR--MTLG---- 546
            ||:|.::.:.|:|....||.                |.|:..|:...|..:|..|  :|.|    
  Rat    52 LGMHNLQAYVRHLKGEQEEA----------------LQSLKEAEALIEGEQLGKRSLVTWGNCAW 100

  Fly   547 ---HRPTMADAHFNLGVVHQKQLNFSS-----------------------------AIPCFRRAI 579
               ||.::|:|...|..|......|||                             |:.||.:|:
  Rat   101 VHYHRGSLAEAQIYLDKVENVCREFSSPFRYRMECAEIDCEEGWALLKCGGSNYMRAMACFAKAL 165

  Fly   580 ELRPQLAVAYLNLGTSLISLGDHRQE------AISVLRTGAR---------------LEGSGVRD 623
            ::.|:  ....|.|.::::   :||:      ::..||...|               |:..|.:|
  Rat   166 QVDPE--NPEYNAGYAVVA---YRQDFDDNHVSLEPLRKAVRLNPEDPHLKVLLALKLQDLGEQD 225

  Fly   624 RG-AHVE---ARYTC----YLQLSVLYRSDGRLQDAAAALRESLKALPL---------LPQKQRA 671
            .. .|:|   :..:|    :...:..:|..|.:.:|...|..:|:..|.         |..||:.
  Rat   226 EAETHIEEALSSTSCQSYVFRYAAKYFRRKGDINEALHLLHRALQTSPSSGYLHYQKGLCYKQQM 290

  Fly   672 V-------LHLRLGEILAELQDWNEAEHQQRLAMQLQPEQGAAYVTYGQTLARNGSRLAEAESWF 729
            :       ...|..|.:.||......|.|:.|  .|:|....|||...:..|..| :..|||..|
  Rat   291 IQLKTSGNRQARRQENIQELAHQAICEFQETL--NLRPTFEMAYVCMAEMQAEIG-QYEEAEGNF 352

  Fly   730 KRALQL----APLEPSSHHHYADFLEQQERH---------HEALGLRLRAAALAPQDYTLQSCVA 781
            :.||.|    |.:|...|..|.   ..|:.|         |...||:|...:.|.:         
  Rat   353 QEALNLNNLVAHIEQDIHFRYG---RSQQFHKKSEDKAITHYLKGLKLEEKSFAWR--------- 405

  Fly   782 DALRLLNRLAEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALEL 837
            ..|..|.::||..:  |:.|.|    ..:.:.||.:.:::|...:|:..|.|||.|
  Rat   406 KLLTALEKVAERRV--RQNVRL----VESTSLLGLVFKLKGQEMKALLYYEKALRL 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150 21/102 (21%)
TPR repeat 518..546 CDD:276809 7/29 (24%)
TPR repeat 551..581 CDD:276809 11/58 (19%)
TPR_1 552..584 CDD:278916 11/60 (18%)
TPR 565..841 CDD:223533 78/360 (22%)
TPR repeat 586..611 CDD:276809 4/30 (13%)
TPR repeat 634..660 CDD:276809 5/29 (17%)
TPR repeat 671..699 CDD:276809 7/34 (21%)
TPR repeat 704..735 CDD:276809 11/30 (37%)
TPR repeat 740..768 CDD:276809 8/36 (22%)
TPR repeat 773..803 CDD:276809 6/29 (21%)
TPR 808..841 CDD:197478 9/30 (30%)
TPR repeat 808..836 CDD:276809 7/27 (26%)
Ifit1NP_064481.1 TPR repeat 136..166 CDD:276809 4/29 (14%)
Coatomer_E 158..421 CDD:252768 62/284 (22%)
TPR repeat 171..203 CDD:276809 6/34 (18%)
TPR repeat 208..236 CDD:276809 5/27 (19%)
TPR repeat 242..270 CDD:276809 4/27 (15%)
TPR repeat 275..324 CDD:276809 10/50 (20%)
TPR repeat 329..356 CDD:276809 9/27 (33%)
TPR repeat 363..396 CDD:276809 8/35 (23%)
TPR repeat 426..454 CDD:276809 7/27 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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