DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tmtc1 and Fkbpl

DIOPT Version :10

Sequence 1:NP_995615.2 Gene:Tmtc1 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_063926.1 Gene:Fkbpl / 56299 MGIID:1932127 Length:347 Species:Mus musculus


Alignment Length:129 Identity:38/129 - (29%)
Similarity:48/129 - (37%) Gaps:29/129 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   735 LAPLEPSSHHHYADFLEQQERHHEAL-------GLRLRAAALAPQDYTLQSCVADALRLLNRLAE 792
            ||.|...|..:..|..|.:....|||       |..|..|. .||.  ...|...|||||     
Mouse   182 LAKLRLDSFTNGRDSWEMEAMEKEALAKEEHRRGTELFRAG-NPQG--AARCYGRALRLL----- 238

  Fly   793 AELWYRKAVTLQPMA----AHAHANLGAILQMRGLRKEAVACYHKALELQPGH--AISRANLAR 850
                    :||.|..    ...:|||.|...:.|..:.|.....:.||.:|||  |:.|..:||
Mouse   239 --------LTLPPPGPPERTTLYANLAACQLLLGHPQLAAQSCDRVLEREPGHLKALYRRGVAR 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tmtc1NP_995615.2 ArnT 11..>209 CDD:441412
TMTC_DUF1736 271..340 CDD:462468
PilF 501..585 CDD:442297
TPR repeat 518..546 CDD:276809
TPR repeat 551..581 CDD:276809
LapB 556..838 CDD:442196 31/113 (27%)
TPR repeat 586..611 CDD:276809
TPR repeat 634..660 CDD:276809
TPR repeat 671..699 CDD:276809
TPR repeat 704..735 CDD:276809 38/129 (29%)
TPR repeat 740..768 CDD:276809 8/34 (24%)
TPR repeat 773..803 CDD:276809 6/29 (21%)
TPR repeat 808..836 CDD:276809 6/27 (22%)
FkbplNP_063926.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
FKBP_N_2 95..>173 CDD:375495
TPR 1 208..241 11/48 (23%)
TPR repeat 208..236 CDD:276809 7/30 (23%)
TPR 212..>336 CDD:440225 29/99 (29%)
TPR repeat 249..279 CDD:276809 7/29 (24%)
TPR 2 250..283 9/32 (28%)
TPR 3 284..317 4/11 (36%)
TPR repeat 284..312 CDD:276809 4/11 (36%)
Blue background indicates that the domain is not in the aligned region.

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