Protein Alignment Tmtc1 and LOC4577322

DIOPT Version :10

• Sequence 1: NP_995615.2
• Gene: Tmtc1 / 33455
• FlyBaseID: FBgn0051690
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_001238468.2
• Gene: LOC4577322 / 4577322
• VectorBaseID: AGAMI1_013727
• Length: 420
• Species: Anopheles gambiae
• Alignment Length: 210
• Identity: 55/210 - (26%)
• Similarity: 76/210 - (36%)
• Gaps: 68/210 - (32%)

  Fly   690 AEHQQRLAMQLQP----EQGAAYVTYGQ----TLARNGSRLAEAESW------FKRALQLA--PL 738
            ::.||.|.....|    ..|...||:.:    |..|.....||.| |      .:||:..|  .|
Mosquito   213 SDQQQELPRPSSPPAIRRSGTLEVTFSERTFVTPKRESMEQAEQE-WTLKQAAARRAVGFADDDL 276

  Fly   739 EPSSHHHYADFLEQ------QERH-----------------HEALGLRLRAAALAPQDYTLQSCV 780
            .|...:  .::|:|      |:|:                 :.||.|...||.||.::|  |.|.
Mosquito   277 RPDERN--PEWLKQRGDTFFQQRNFLAAISAYSAGIRLTKDYYALFLNRSAAHLALENY--QRCA 337

  Fly   781 AD---ALRLL------NRLAEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALE 836
            .|   ||.||      ||.|......|:|..|        ..||.:.|  |. :|.:|    |..
Mosquito   338 EDCSTALELLQPPVEANRRARVACLARRAAAL--------VKLGFLQQ--GY-EEMIA----ASR 387

  Fly   837 LQPGHAISRANLARM 851
            |.|..|..|..:.|:
Mosquito   388 LDPDEASLRLEVDRL 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmtc1	NP_995615.2	ArnT	11..>209	CDD:441412
		TMTC_DUF1736	271..340	CDD:462468
		PilF	501..585	CDD:442297
		TPR repeat	518..546	CDD:276809
		TPR repeat	551..581	CDD:276809
		LapB	556..838	CDD:442196	50/195 (26%)
		TPR repeat	586..611	CDD:276809
		TPR repeat	634..660	CDD:276809
		TPR repeat	671..699	CDD:276809	3/8 (38%)
		TPR repeat	704..735	CDD:276809	11/40 (28%)
		TPR repeat	740..768	CDD:276809	9/50 (18%)
		TPR repeat	773..803	CDD:276809	13/38 (34%)
		TPR repeat	808..836	CDD:276809	7/27 (26%)
LOC4577322	XP_001238468.2	None