DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and IFIT3

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_001026853.1 Gene:IFIT3 / 3437 HGNCID:5411 Length:490 Species:Homo sapiens


Alignment Length:246 Identity:49/246 - (19%)
Similarity:89/246 - (36%) Gaps:48/246 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   627 HVEARYTCYLQLSVLYRSDGRLQDAAAALRESLKALPLLPQKQRAVLHLRLGEILAELQDWNEAE 691
            :.|.:.|.|..|:.:...||..:.|...||:   |..|:.|:     |....|| ..|..|....
Human    46 NTEFKATMYNLLAYIKHLDGNNEAALECLRQ---AEELIQQE-----HADQAEI-RSLVTWGNYA 101

  Fly   692 ----HQQRLA------------------------MQLQPEQGAAYVTYGQTLARNGSRLAEAESW 728
                |..||:                        .:|..|:|...:..|        |...|:..
Human   102 WVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCG--------RNERAKVC 158

  Fly   729 FKRALQLAPLEPSSHHHYADFLEQQERHHE---ALGLRLRAAALAPQDYTLQSCVADALRLLNRL 790
            |::||:..|..|......|..:...:.|.|   :..:..:|..|:|.:..::..:...|:.:|:.
Human   159 FEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKE 223

  Fly   791 AEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALELQPGH 841
            ||.|.:..:|:...|.......:.....:.:|...:|:..:.:.||..|.:
Human   224 AEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNN 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150
TPR repeat 518..546 CDD:276809
TPR repeat 551..581 CDD:276809
TPR_1 552..584 CDD:278916
TPR 565..841 CDD:223533 49/244 (20%)
TPR repeat 586..611 CDD:276809
TPR repeat 634..660 CDD:276809 7/25 (28%)
TPR repeat 671..699 CDD:276809 8/55 (15%)
TPR repeat 704..735 CDD:276809 7/30 (23%)
TPR repeat 740..768 CDD:276809 5/30 (17%)
TPR repeat 773..803 CDD:276809 6/29 (21%)
TPR 808..841 CDD:197478 5/32 (16%)
TPR repeat 808..836 CDD:276809 2/27 (7%)
IFIT3NP_001026853.1 TPR_12 51..126 CDD:290160 19/83 (23%)
TPR 1 51..84 10/35 (29%)
TPR repeat 51..79 CDD:276809 9/30 (30%)
TPR repeat 84..123 CDD:276809 8/44 (18%)
TPR 2 94..127 5/32 (16%)
TPR 3 136..169 10/40 (25%)
TPR repeat 136..164 CDD:276809 8/35 (23%)
TPR_19 150..213 CDD:291240 14/70 (20%)
TPR 4 172..206 6/33 (18%)
PRK02603 184..341 CDD:179448 17/91 (19%)
TPR repeat 206..236 CDD:276809 6/29 (21%)
TPR 5 207..240 7/32 (22%)
TPR 6 241..274 5/32 (16%)
TPR repeat 241..269 CDD:276809 2/27 (7%)
TPR 7 415..448
TPR 8 450..481
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 467..490
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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