DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31690 and ogt.1

DIOPT Version :9

Sequence 1:	NP_995615.2	Gene:	CG31690 / 33455	FlyBaseID:	FBgn0051690	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001017359.1	Gene:	ogt.1 / 337685	ZFINID:	ZDB-GENE-030131-9631	Length:	1062	Species:	Danio rerio

Alignment Length:	465	Identity:	123/465 - (26%)
Similarity:	184/465 - (39%)	Gaps:	107/465 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 SAIYSTSSKSKSASWTAAPILGTAFLVLPFLPASNLLFYVGFVMAERVLYLPSVGYCLLFGLGFG 464
            ||.:||.:..::      |:|..|:        |||    |.|..||                 |
Zfish    74 SAHFSTLAIKQN------PMLAEAY--------SNL----GNVYKER-----------------G 103

  Fly   465 HLWQRVNSSWRSRLML-------LCGLALLLGVHGVRTFRRNLDWRDEEQLFRSAISINPPK--A 520
            .| |.....:|..|.|       ...||..|...|        |.....|.:.||:..||..  .
Zfish   104 QL-QEAIEHYRHALRLKPDFIDGYINLAAALVAAG--------DMEGAVQAYVSALQYNPDLYCV 159

  Fly   521 LGNLGSVLSAQGRYEEAELTLRMTLGHRPTMADAHFNLGVVHQKQLNFSSAIPCFRRAIELRPQL 585
            ..:||::|.|.||.|||:......:..:|..|.|..|||.|...|.....||..|.:|:.|.|..
Zfish   160 RSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF 224

  Fly   586 AVAYLNLGTSLISLGDHRQEAISVLRTGARLEGSGVRDRGAHVEARYTCYLQLSVLYRSDGRLQD 650
            ..||:|||..|                                               .:.|:.|
Zfish   225 LDAYINLGNVL-----------------------------------------------KEARIFD 242

  Fly   651 AAAALRESLKALPLLPQKQRAVLHLRLGEILAELQDWNEAEHQQRLAMQLQPEQGAAYVTYGQTL 715
            .|.|  ..|:||.|.|  ..||:|..|..:..|....:.|....|.|::|||....||......|
Zfish   243 RAVA--GYLRALSLSP--NHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 303

  Fly   716 ARNGSRLAEAESWFKRALQLAPLEPSSHHHYADFLEQQERHHEALGLRLRAAALAPQDYTLQSCV 780
            ...|: ::|||..:..||:|.|....|.::.|:...:|....||:.|..:|..:.|:.....|.:
Zfish   304 KEKGN-VSEAEECYNTALRLCPTHADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNL 367

  Fly   781 ADALRLLNRLAEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALELQPGHAISR 845
            |..|:...:|.||.:.|::|:.:.|..|.|::|:|..|:.....:.|:.||.:|:::.|..|.:.
Zfish   368 ASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAH 432

  Fly   846 ANLARMNVHK 855
            :|||  ::||
Zfish   433 SNLA--SIHK 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31690	NP_995615.2	DUF1736	272..340	CDD:285594
		TPR_11	518..583	CDD:290150	22/66 (33%)
		TPR repeat	518..546	CDD:276809	9/29 (31%)
		TPR repeat	551..581	CDD:276809	11/29 (38%)
		TPR_1	552..584	CDD:278916	12/31 (39%)
		TPR	565..841	CDD:223533	71/275 (26%)
		TPR repeat	586..611	CDD:276809	6/24 (25%)
		TPR repeat	634..660	CDD:276809	4/25 (16%)
		TPR repeat	671..699	CDD:276809	8/27 (30%)
		TPR repeat	704..735	CDD:276809	9/30 (30%)
		TPR repeat	740..768	CDD:276809	7/27 (26%)
		TPR repeat	773..803	CDD:276809	8/29 (28%)
		TPR	808..841	CDD:197478	10/32 (31%)
		TPR repeat	808..836	CDD:276809	9/27 (33%)
ogt.1	NP_001017359.1	TPR	20..285	CDD:223533	75/305 (25%)
		TPR repeat	24..49	CDD:276809
		TPR repeat	57..83	CDD:276809	4/8 (50%)
		TPR_1	89..122	CDD:278916	14/62 (23%)
		TPR repeat	89..117	CDD:276809	12/57 (21%)
		TPR repeat	122..152	CDD:276809	8/37 (22%)
		TPR repeat	157..185	CDD:276809	9/27 (33%)
		TPR_1	163..190	CDD:278916	10/26 (38%)
		TPR_1	191..224	CDD:278916	13/32 (41%)
		TPR repeat	191..219	CDD:276809	11/27 (41%)
		TPR	204..461	CDD:223533	77/291 (26%)
		TPR_17	213..246	CDD:290167	13/79 (16%)
		TPR repeat	226..253	CDD:276809	12/75 (16%)
		TPR repeat	259..287	CDD:276809	8/27 (30%)
		SNAP	276..430	CDD:305195	44/154 (29%)
		TPR repeat	290..322	CDD:276937	10/32 (31%)
		TPR_1	293..326	CDD:278916	11/33 (33%)
		TPR repeat	293..321	CDD:276809	8/28 (29%)
		TPR repeat	323..358	CDD:276937	8/34 (24%)
		TPR repeat	326..356	CDD:276809	7/29 (24%)
		TPR repeat	361..389	CDD:276809	8/27 (30%)
		TPR repeat	362..402	CDD:276937	12/39 (31%)
		TPR repeat	395..423	CDD:276809	9/27 (33%)
		TPR_1	429..462	CDD:278916	6/14 (43%)
		TPR repeat	429..457	CDD:276809	6/14 (43%)
		Glyco_transf_41	556..1038	CDD:290556
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910