DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31690 and Spag1

DIOPT Version :9

Sequence 1:	NP_995615.2	Gene:	CG31690 / 33455	FlyBaseID:	FBgn0051690	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001012116.1	Gene:	Spag1 / 315033	RGDID:	1310702	Length:	893	Species:	Rattus norvegicus

Alignment Length:	386	Identity:	86/386 - (22%)
Similarity:	119/386 - (30%)	Gaps:	142/386 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   516 NPPKALGNLGSVLSAQGRYEEAELTLRMTLGHRPTMADAHFNLGVVHQKQLNFSSAIPCFRRAIE 580
            |..|..||....   .|.||||.:....:|...|| |.|:.|......|...:|||:....:|:|
  Rat   214 NREKGKGNEAFY---SGDYEEAVMYYTRSLSALPT-ATAYNNRAQAEIKLQRWSSALEDCEKALE 274

  Fly   581 LRP-------QLAVAYLNLGTSLISLGDHRQ-------------------------EAISVLRT- 612
            |.|       :.|..|.:....|.::.|.|:                         |..|.|:|
  Rat   275 LEPGNIKALLRRATTYKHQNKFLEAVDDLRKVLQAEPDNDLAKKTLSEVERELKNSEPASELQTK 339

  Fly   613 GARL-----EGSGVRDRGAH----------VEARYTCYLQLSVLYRSDGRLQDAAAALRESLKAL 662
            |.|:     |.||  |.|..          |:......:|..::.||.|.        |.|.:|.
  Rat   340 GKRMVIEEVENSG--DEGGKGDEDDHEDDGVDMAAMGNIQKKLMVRSQGG--------RRSRRAR 394

  Fly   663 PLLPQKQRAVLHLRLGEILAELQDWNEAEHQQRLAMQLQPEQGAAYV------------------ 709
            ..:|                      .||.|:.     |||.|.|..
  Rat   395 TPMP----------------------GAEQQEG-----QPETGTASTSDNHDLEERRAADSPGDL 432

  Fly   710 -TYGQTLARNGSRLAEAESWFKRALQLAPLEPSSHHHYADFLEQQERHHEALGLRLRAAALAPQD 773
             :.|..|.| |.:.|||...:..|  :|.|||:.          .|...|...|....||...::
  Rat   433 KSRGNELFR-GGQFAEAAVQYSGA--IAQLEPTG----------SENADELSILYSNRAACYLKE 484

  Fly   774 YTLQSCVADALRLLNRLAEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKA 834
            ...:.|:.|..|              |:.|||.|...       |..|.:..|.:..|..|
  Rat   485 GNCRGCIQDCDR--------------ALELQPFAVKP-------LLRRAMAYETLEQYRSA 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31690	NP_995615.2	DUF1736	272..340	CDD:285594
		TPR_11	518..583	CDD:290150	21/64 (33%)
		TPR repeat	518..546	CDD:276809	8/27 (30%)
		TPR repeat	551..581	CDD:276809	8/29 (28%)
		TPR_1	552..584	CDD:278916	11/38 (29%)
		TPR	565..841	CDD:223533	70/337 (21%)
		TPR repeat	586..611	CDD:276809	7/49 (14%)
		TPR repeat	634..660	CDD:276809	6/25 (24%)
		TPR repeat	671..699	CDD:276809	3/27 (11%)
		TPR repeat	704..735	CDD:276809	10/49 (20%)
		TPR repeat	740..768	CDD:276809	4/27 (15%)
		TPR repeat	773..803	CDD:276809	4/29 (14%)
		TPR	808..841	CDD:197478	5/27 (19%)
		TPR repeat	808..836	CDD:276809	5/27 (19%)
Spag1	NP_001012116.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..155
		3a0801s09	141..>303	CDD:273380	26/92 (28%)
		TPR 1	213..246		12/35 (34%)
		TPR repeat	217..241	CDD:276809	8/26 (31%)
		TPR repeat	246..275	CDD:276809	8/28 (29%)
		TPR 2	247..279		10/31 (32%)
		TPR 3	280..313		5/32 (16%)
		TPR repeat	280..308	CDD:276809	5/27 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..344		6/19 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	349..368		5/20 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	373..437		16/98 (16%)
		TPR 4	429..463		12/36 (33%)
		3a0801s09	<432..>569	CDD:273380	30/127 (24%)
		TPR repeat	432..458	CDD:276809	8/28 (29%)
		TPR repeat	466..500	CDD:276809	8/47 (17%)
		TPR 5	471..504		10/46 (22%)
		TPR repeat	505..533	CDD:276809	5/27 (19%)
		TPR 6	506..538		5/26 (19%)
		3a0801s09	569..>695	CDD:273380
		TPR 7	605..638
		TPR repeat	606..633	CDD:276809
		TPR repeat	638..668	CDD:276809
		TPR 8	639..672
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..756
		RPAP3_C	769..858	CDD:404718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900