DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and KDM6B

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_001073893.1 Gene:KDM6B / 23135 HGNCID:29012 Length:1682 Species:Homo sapiens


Alignment Length:135 Identity:35/135 - (25%)
Similarity:43/135 - (31%) Gaps:49/135 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   736 APLEPS--------SHHHYADFLEQQERHHEALGLRLRAAALAPQDYTLQSCVADALRLLNRLAE 792
            |||.||        |..:||.........|..|             .:|..||.   .||...|:
Human    58 APLPPSHGSSSGHPSKPYYAPGAPTPRPLHGKL-------------ESLHGCVQ---ALLREPAQ 106

  Fly   793 AELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKAL-------ELQPGHAISRANLAR 850
            ..||               ..||.:.:.....:||..|||.||       ||.|  .|.|...|:
Human   107 PGLW---------------EQLGQLYESEHDSEEATRCYHSALRYGGSFAELGP--RIGRLQQAQ 154

  Fly   851 M-NVH 854
            : |.|
Human   155 LWNFH 159

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150
TPR repeat 518..546 CDD:276809
TPR repeat 551..581 CDD:276809
TPR_1 552..584 CDD:278916
TPR 565..841 CDD:223533 30/119 (25%)
TPR repeat 586..611 CDD:276809
TPR repeat 634..660 CDD:276809
TPR repeat 671..699 CDD:276809
TPR repeat 704..735 CDD:276809
TPR repeat 740..768 CDD:276809 7/35 (20%)
TPR repeat 773..803 CDD:276809 8/29 (28%)
TPR 808..841 CDD:197478 12/39 (31%)
TPR repeat 808..836 CDD:276809 9/34 (26%)
KDM6BNP_001073893.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 52..88 8/29 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 190..680
Mito_fiss_reg <566..640 CDD:283069
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 704..807
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 822..1096
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1288..1325
JmjC 1343..1407 CDD:214721
JmjC 1377..1485 CDD:202224
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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