DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and Kdm6a

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:XP_006527657.1 Gene:Kdm6a / 22289 MGIID:1095419 Length:1476 Species:Mus musculus


Alignment Length:433 Identity:91/433 - (21%)
Similarity:140/433 - (32%) Gaps:128/433 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   345 KGSGLRSAASPMDFAEVANISLPLLRRL--------GGNSCHTWLGLTCDC-------------- 387
            |.||....|||...||.......|..||        .|......||....|              
Mouse    31 KASGESEEASPSLTAEEREALGGLDSRLFGFVRFHEDGARMKALLGKAVRCYESLILKAEGKVES 95

  Fly   388 -------HHQLSAPSYRSASAIYSTSSKSKSASWTAAPILGTAFLVLPFLPASNLLF--YVGFVM 443
                   |..|....|..|.:.|......:|..|..|          .||....|::  |..|..
Mouse    96 DFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNA----------AFLYGLGLVYFHYNAFQW 150

  Fly   444 A----ERVLYL-PSVGYC------LLFGLGFGHLWQRVNSSWRSRL------MLLCGLALLLGV- 490
            |    :.|||: ||  :|      |..||.|     :||:.:.|.|      ::.|....|... 
Mouse   151 AIKAFQEVLYVDPS--FCRAKEIHLRLGLMF-----KVNTDYESSLKHFQLALVDCNPCTLSNAE 208

  Fly   491 ---------------HGVR------------------TFRRNLDWRDEE---------------Q 507
                           |..:                  |..:.|.|....               |
Mouse   209 IQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATILQQLGWMHHTVDLLGDKATKESYAIQ 273

  Fly   508 LFRSAISINPPKALG--NLGSVLSAQGRYEEAELTLRMTLGHRPTMADAHFNLGVVHQKQLNFSS 570
            ..:.::..:|.....  .||...|:.|:.::|.::.|.::......||...::||::|:|.....
Mouse   274 YLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMD 338

  Fly   571 AIPCFRRAIELRPQLAVAYLNLGTSLISLGDHRQEAISVLRTGARLEG-SGVRDRGAHVEARYTC 634
            |:..:..|::|....|.|:::||| |....:..|:||.......|.:. |......|.::     
Mouse   339 ALQAYICAVQLDHGHAAAWMDLGT-LYESCNQPQDAIKCYLNATRSKNCSNTSGLAARIK----- 397

  Fly   635 YLQLSVLYRSDGRLQDAAAALR--ESLKALPL---LPQKQRAV 672
            |||..:.....|.||:....|.  |...:||:   |..:|.|:
Mouse   398 YLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAM 440

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150 15/66 (23%)
TPR repeat 518..546 CDD:276809 6/29 (21%)
TPR repeat 551..581 CDD:276809 8/29 (28%)
TPR_1 552..584 CDD:278916 9/31 (29%)
TPR 565..841 CDD:223533 29/114 (25%)
TPR repeat 586..611 CDD:276809 9/24 (38%)
TPR repeat 634..660 CDD:276809 8/27 (30%)
TPR repeat 671..699 CDD:276809 1/2 (50%)
TPR repeat 704..735 CDD:276809
TPR repeat 740..768 CDD:276809
TPR repeat 773..803 CDD:276809
TPR 808..841 CDD:197478
TPR repeat 808..836 CDD:276809
Kdm6aXP_006527657.1 TPR repeat 95..123 CDD:276809 5/27 (19%)
TPR 108..401 CDD:223533 63/315 (20%)
TPR repeat 131..161 CDD:276809 9/39 (23%)
TPR repeat 166..196 CDD:276809 9/34 (26%)
TPR repeat 207..235 CDD:276809 1/27 (4%)
TPR repeat 287..314 CDD:276809 6/26 (23%)
TPR repeat 319..349 CDD:276809 8/29 (28%)
TPR repeat 354..380 CDD:276809 9/26 (35%)
JmjC 1151..1215 CDD:214721
JmjC 1185..1293 CDD:334913
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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