DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and LONRF2

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_940863.3 Gene:LONRF2 / 164832 HGNCID:24788 Length:754 Species:Homo sapiens


Alignment Length:238 Identity:58/238 - (24%)
Similarity:82/238 - (34%) Gaps:86/238 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   660 KALPLLPQKQRAVLHLRLG--EILAELQDWNEAEHQQRLAMQLQPEQGAAYVTYGQTLARNGSRL 722
            :|.|:..:.:......|.|  |:.|||       .:..||...||::|.. :..|..|||.| ||
Human    19 RAEPIAQRLEEGDEAFRAGDYEMAAEL-------FRSMLAGLAQPDRGLC-LRLGDALARAG-RL 74

  Fly   723 AEAESWFKRALQLAPLEPSSHHHYADFLEQQERHHEALGLRLRAAAL------------------ 769
            .||...|:.|.:|..|.|......|..|.:      |:|||.|..:.                  
Human    75 PEALGAFRGAARLGALRPEELEELAGGLVR------AVGLRDRPLSAENPGGEPEAPGEGGPAPE 133

  Fly   770 --APQDYTLQSCVADALRLLNRLAEAELWYRKAVTL----------------QPMAAHAHANLGA 816
              ||:|  |..| ....|||:          |.|||                :|.....:..|..
Human   134 PRAPRD--LLGC-PRCRRLLH----------KPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSG 185

  Fly   817 IL---------------QMRGLRKE-----AVACYHKALELQP 839
            :|               |.|.|:::     |:....:||||.|
Human   186 LLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQALELAP 228

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150
TPR repeat 518..546 CDD:276809
TPR repeat 551..581 CDD:276809
TPR_1 552..584 CDD:278916
TPR 565..841 CDD:223533 58/238 (24%)
TPR repeat 586..611 CDD:276809
TPR repeat 634..660 CDD:276809 58/238 (24%)
TPR repeat 671..699 CDD:276809 8/29 (28%)
TPR repeat 704..735 CDD:276809 12/30 (40%)
TPR repeat 740..768 CDD:276809 8/27 (30%)
TPR repeat 773..803 CDD:276809 8/29 (28%)
TPR 808..841 CDD:197478 11/52 (21%)
TPR repeat 808..836 CDD:276809 7/47 (15%)
LONRF2NP_940863.3 TPR 1 23..58 10/41 (24%)
TPR_16 27..92 CDD:372602 24/73 (33%)
TPR 2 59..91 13/33 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 112..136 0/23 (0%)
RING1-HC_LONFs 143..174 CDD:319427 8/41 (20%)
TPR 3 197..230 9/32 (28%)
TPR repeat 200..225 CDD:276809 5/24 (21%)
TPR repeat 230..260 CDD:276809
TPR 4 231..264
TPR repeat 265..293 CDD:276809
TPR 5 266..298
PEX10 <380..489 CDD:227861
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 398..439
RING2-HC_LONFs 446..487 CDD:319428
TPR 6 447..483
RING-HC finger (C3HC4-type) 449..486 CDD:319428
LON_substr_bdg 538..738 CDD:366967
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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