DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and Ifit2

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_001342191.1 Gene:Ifit2 / 15958 MGIID:99449 Length:470 Species:Mus musculus


Alignment Length:270 Identity:53/270 - (19%)
Similarity:105/270 - (38%) Gaps:88/270 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   572 IPCFRRAIELRPQLAVAYLNLGTSLISLGDHRQEAISVLRTGARLEGSGV----RDRGAHVEARY 632
            |....:||:|.|......:.|...|.::  |:.:|::::....:.:.|.:    |      .||:
Mouse   195 IDSLEQAIQLSPDNTYVKVLLALKLDAV--HKNQAMALVEEALKKDPSAIDTLLR------AARF 251

  Fly   633 TCYLQLSVLYRSDGRLQDAAAALRESLKALP-------------------LLPQK---------- 668
            .|     .:|.:|..:|    .||::|:.||                   :|.::          
Mouse   252 YC-----KVYDTDRAIQ----LLRKALEKLPNNAYVHYYMGCCYRSKVHHMLNRREMVFSGDRKK 307

  Fly   669 -----QRAVLHLRLGEILAELQDWNEAEHQQRLAMQLQPEQGAAYVTYGQTLARNGSRLAEAESW 728
                 |.||.|||..|.:.|:.:::                 .:::.....:|:   :..||:.:
Mouse   308 LEELIQLAVNHLRKAEEIKEMLEYS-----------------CSFLADLYIIAK---KYDEADYY 352

  Fly   729 FKRALQL-APLEPSS--HHHYADF----LEQQER--HHEALGLRLRAAALAPQDYTLQSCVADAL 784
            |::.|.. .|..|..  |..|.:|    :::|::  :|...|::::...: ||....:.....||
Mouse   353 FQKELSKDLPPGPKQLLHLRYGNFQFFQMKRQDKAIYHYMEGVKIKKKTI-PQKKMREKLQRIAL 416

  Fly   785 RLLNRLAEAE 794
            |   ||.|.|
Mouse   417 R---RLHEDE 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150 4/10 (40%)
TPR repeat 518..546 CDD:276809
TPR repeat 551..581 CDD:276809 3/8 (38%)
TPR_1 552..584 CDD:278916 4/11 (36%)
TPR 565..841 CDD:223533 53/270 (20%)
TPR repeat 586..611 CDD:276809 4/24 (17%)
TPR repeat 634..660 CDD:276809 6/25 (24%)
TPR repeat 671..699 CDD:276809 7/27 (26%)
TPR repeat 704..735 CDD:276809 5/30 (17%)
TPR repeat 740..768 CDD:276809 7/35 (20%)
TPR repeat 773..803 CDD:276809 7/22 (32%)
TPR 808..841 CDD:197478
TPR repeat 808..836 CDD:276809
Ifit2NP_001342191.1 TPR 1 51..89
TPR 2 90..135
TPR repeat 96..122 CDD:276809
TPR repeat 127..167 CDD:276809
TPR 3 136..171
PEP_TPR_lipo <145..359 CDD:274350 36/200 (18%)
TPR 4 172..208 5/12 (42%)
TPR 5 242..275 12/47 (26%)
TPR repeat 242..270 CDD:276809 9/42 (21%)
TPR repeat 275..325 CDD:276809 8/49 (16%)
TPR 6 276..331 9/54 (17%)
TPR repeat 330..358 CDD:276809 4/47 (9%)
TPR 7 332..362 5/49 (10%)
TPR 8 363..401 7/37 (19%)
TPR 9 402..443 9/26 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 439..470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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