DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31690 and Ifit1

DIOPT Version :9

Sequence 1:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster
Sequence 2:NP_032357.2 Gene:Ifit1 / 15957 MGIID:99450 Length:463 Species:Mus musculus


Alignment Length:446 Identity:94/446 - (21%)
Similarity:167/446 - (37%) Gaps:138/446 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   488 LGVHGVRTFRRNLDWRDEEQLFRSAISINPPKALGNLGSVLSAQGRYEEAELTLR--MTLG---- 546
            ||:|.:..:.|:|..:.:|.                |.|:..|:...:..:|:.|  .|.|    
Mouse    52 LGMHNLLAYVRHLKGQQDEA----------------LQSLKEAEALIQSEQLSKRSLATWGNCAW 100

  Fly   547 ---HRPTMADAHFNLGVVHQKQLNFSS-----------------------------AIPCFRRAI 579
               ||.::|:|...|..|.:....|||                             |:.||.:|:
Mouse   101 LHYHRGSLAEAQIYLDKVEKVCKEFSSPFRYRLECAEMDCEEGWALLKCGGGNYKQAMACFAKAL 165

  Fly   580 ELRPQLAVAYLNLGTSLISLGDHRQE------AISVLRTGARLEGSG----------VRDRGAHV 628
            ::.|:  ....|.|.::::   :||:      ::..||...||....          ::|.|.||
Mouse   166 KVEPE--NPEYNTGYAVVA---YRQDLDDNFISLEPLRKAVRLNPEDPYLKVLLALKLQDLGEHV 225

  Fly   629 EA------------------RYTCYLQLSVLYRSDGRLQDAAAALRESLKALPLLPQKQRAVLHL 675
            ||                  ||.     :..:|...|:..|...|..:|:|.|     ....||.
Mouse   226 EAEAHIEEALSSTSCQSYVIRYA-----AKYFRRKHRVDKALHLLNRALQASP-----SSGYLHY 280

  Fly   676 RLG----EILAEL----------QD-----WNEAEHQQRLAMQLQPEQGAAYVTYGQTLARNGSR 721
            :.|    :.:::|          ||     ..:|.|:.:..::|:|....|||...:..|.. .:
Mouse   281 QKGLCYKQQISQLRTSRNRQPRRQDNVQELAQQAIHEFQETLKLRPTFEMAYVCMAEVQAEI-HQ 344

  Fly   722 LAEAESWFKRALQ----LAPLEPSSHHHYADFLE-QQERHHEALGLRLRAAALAPQDYTLQSCVA 781
            ..|||..|::||.    :|.:|...|..|..||: .::...:|:.|.|:...:..:.:..:.   
Mouse   345 YEEAERNFQKALNNKTLVAHIEQDIHLRYGRFLQFHKQSEDKAITLYLKGLKVEEKSFAWRK--- 406

  Fly   782 DALRLLNRLAEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALEL 837
             .|..|.::||      :.|........:.:.||.:.:::|..|.|:..|.|||.|
Mouse   407 -LLTALEKVAE------RRVCQNVHLVESTSLLGLVYKLKGQEKNALFYYEKALRL 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150 20/102 (20%)
TPR repeat 518..546 CDD:276809 6/29 (21%)
TPR repeat 551..581 CDD:276809 11/58 (19%)
TPR_1 552..584 CDD:278916 11/60 (18%)
TPR 565..841 CDD:223533 75/360 (21%)
TPR repeat 586..611 CDD:276809 4/30 (13%)
TPR repeat 634..660 CDD:276809 4/25 (16%)
TPR repeat 671..699 CDD:276809 8/46 (17%)
TPR repeat 704..735 CDD:276809 10/34 (29%)
TPR repeat 740..768 CDD:276809 7/28 (25%)
TPR repeat 773..803 CDD:276809 5/29 (17%)
TPR 808..841 CDD:197478 10/30 (33%)
TPR repeat 808..836 CDD:276809 8/27 (30%)
Ifit1NP_032357.2 TPR 1 52..85 9/48 (19%)
TPR_12 54..124 CDD:290160 17/85 (20%)
TPR repeat 55..86 CDD:276809 7/46 (15%)
TPR repeat 91..121 CDD:276809 8/29 (28%)
TPR 2 92..126 8/33 (24%)
TPR 3 136..171 5/36 (14%)
TPR repeat 136..166 CDD:276809 4/29 (14%)
TPR_16 145..208 CDD:290168 13/67 (19%)
TPR repeat 171..203 CDD:276809 6/34 (18%)
TPR 4 174..207 8/35 (23%)
type_IV_pilW <194..354 CDD:131573 37/170 (22%)
TPR repeat 208..236 CDD:276809 6/27 (22%)
TPR 5 209..241 6/31 (19%)
TPR 6 242..275 9/42 (21%)
TPR repeat 242..270 CDD:276809 6/32 (19%)
Interaction with the 5'-triphosphate group of PPP-RNA. /evidence=ECO:0000250 247..253 1/10 (10%)
TPR repeat 275..324 CDD:276809 8/48 (17%)
TPR 7 294..328 6/33 (18%)
TPR 8 329..362 10/33 (30%)
TPR repeat 329..356 CDD:276809 8/27 (30%)
TPR 9 367..401 7/33 (21%)
TPR 10 426..459 10/30 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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