DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31690 and ifit5

DIOPT Version :9

Sequence 1:	NP_995615.2	Gene:	CG31690 / 33455	FlyBaseID:	FBgn0051690	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001135660.1	Gene:	ifit5 / 100216220	XenbaseID:	XB-GENE-5842099	Length:	473	Species:	Xenopus tropicalis

Alignment Length:	297	Identity:	59/297 - (19%)
Similarity:	105/297 - (35%)	Gaps:	63/297 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   507 QLFRSAISINPPKALGNLGSVLSAQ--GRYEEAELTLRMTLGHRPTMADAHFNLGVVHQKQLNFS 569
            ||...|:.:||..::..:...|..|  .|.|||...::..|...|.:......:...:::...|.
Frog   201 QLLERAVKLNPKDSVIKVLLALKLQELKRQEEAMKHIKDALELTPDLPYVLRYVAKFYRRAGKFE 265

  Fly   570 SAIPCFRRAIELRPQLAVAYLNLGTSLISLGDHRQEAISVLRTGARLEGSGVRDRGAHVEARYTC 634
            ..|...::|:.:.|.....:..||..      :||..|...|||               :|.|
Frog   266 ETIRVLKKAVSITPNSGFLHHQLGLC------YRQMIIQRKRTG---------------KANY-- 307

  Fly   635 YLQLSVLYRSDGRLQDAAAALRESLKAL---PLLPQKQRAVLHLR--LGEILAELQDWNEAEHQQ 694
                        |.||.......:.||:   .:..:.::..||..  |.::......:.:||...
Frog   308 ------------RGQDTQEIKDLTEKAIFHFEMALEMKKTFLHAHFDLADMYVRSNQYQKAEETY 360

  Fly   695 RLAMQL----QPEQGAAYVTYGQTLARNGSRLAEAESWFKRALQLAPLEPSSHHHYADFLEQQER 755
            :.|.:|    :.|:..|::.||:.|..:.....||...:|..|:               :..|..
Frog   361 KKATELITTPEHEKQQAHLQYGKFLENSKKSEDEAVEQYKEGLR---------------IPDQNT 410

  Fly   756 HHEALGLRLRAAALAPQDYTLQSCVADALRLLNRLAE 792
            |.:...:.||  .:|.|.....|....||.||..:::
Frog   411 HRQECEMCLR--RIANQRLARNSRDTSALALLGFISK 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31690	NP_995615.2	DUF1736	272..340	CDD:285594
		TPR_11	518..583	CDD:290150	11/66 (17%)
		TPR repeat	518..546	CDD:276809	6/29 (21%)
		TPR repeat	551..581	CDD:276809	3/29 (10%)
		TPR_1	552..584	CDD:278916	3/31 (10%)
		TPR	565..841	CDD:223533	46/237 (19%)
		TPR repeat	586..611	CDD:276809	5/24 (21%)
		TPR repeat	634..660	CDD:276809	3/25 (12%)
		TPR repeat	671..699	CDD:276809	6/29 (21%)
		TPR repeat	704..735	CDD:276809	8/30 (27%)
		TPR repeat	740..768	CDD:276809	4/27 (15%)
		TPR repeat	773..803	CDD:276809	5/20 (25%)
		TPR	808..841	CDD:197478
		TPR repeat	808..836	CDD:276809
ifit5	NP_001135660.1	PEP_TPR_lipo	<144..>405	CDD:274350	48/253 (19%)
		TPR repeat	219..242	CDD:276809	6/22 (27%)
		TPR repeat	248..276	CDD:276809	3/27 (11%)
		TPR repeat	281..332	CDD:276809	15/85 (18%)
		TPR repeat	337..365	CDD:276809	6/27 (22%)
		TPR repeat	375..404	CDD:276809	7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910