DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf4 and Tbpl1

DIOPT Version :9

Sequence 1:	NP_608699.1	Gene:	Trf4 / 33452	FlyBaseID:	FBgn0031444	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_035733.1	Gene:	Tbpl1 / 237336	MGIID:	1339946	Length:	186	Species:	Mus musculus

Alignment Length:	158	Identity:	38/158 - (24%)
Similarity:	70/158 - (44%)	Gaps:	2/158 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 AEIEEKLELHFRPFTCVMDFNCRFSMYELCLLLAESRFDPSSHPSVVVKITHPSAQVKIHAGGKI 177
            |:.:..|::......||....|..::.::.|..|...: ......|::|:..|.....|.:.|||
Mouse     3 ADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIY-KRDVGKVLMKLRKPRITATIWSSGKI 66

  Fly   178 SST-ALNADSARSGLFKVIRILQDLDYKVDIMNFSKNIVNASFSMPFKIDLDLMSRRHVVEVAQN 241
            ..| |.:.:.|:.|..::.|.||.|.::|...:|....|.|..:|||:|.|...::.:....:..
Mouse    67 ICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYE 131

  Fly   242 RSRRPFITYTTENLGVRFAVFPTGFVLV 269
            ....|.:.|..::|.....:|.||.:.|
Mouse   132 PELHPAVCYRIKSLRATLQIFSTGSITV 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf4	NP_608699.1	TBP	128..200	CDD:278767	18/72 (25%)
		PLN00062	131..294	CDD:177693	34/140 (24%)
		TBP	213..291	CDD:278767	14/57 (25%)
Tbpl1	NP_035733.1	TLF	9..180	CDD:239953	37/152 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770