DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta4R2 and PRE5

DIOPT Version :9

Sequence 1:	NP_001259950.1	Gene:	Prosbeta4R2 / 33451	FlyBaseID:	FBgn0031443	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_014045.1	Gene:	PRE5 / 855362	SGDID:	S000004931	Length:	234	Species:	Saccharomyces cerevisiae

Alignment Length:	144	Identity:	33/144 - (22%)
Similarity:	57/144 - (39%)	Gaps:	27/144 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AMETILGIKGPDFVMLASDTMQAKSLVFMKDD-------QSKIHRLSDFNMMATVGDGGDTIQFT 59
            |:|.|.  :|...|.|.|:|...  ||.:|.:       |.||.:..:...::..|...|....:
Yeast    25 ALEAIK--QGSVTVGLRSNTHAV--LVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVLS 85

  Fly    60 DFISKNLHLYKISHGYHLSAKSAAHFTRKTLADYIRTNTR------YQVAMLLAGYDAVEG---- 114
            :::.:..:...:.....|:.:.|.|.    |.|..:.||:      |.|.:|:.|||....
Yeast    86 NYLRQQCNYSSLVFNRKLAVERAGHL----LCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLE 146

  Fly   115 --PDLHYIDSYGAA 126
              |..:..:.||.|
Yeast   147 FQPSGNVTELYGTA 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta4R2	NP_001259950.1	PRE1	1..194	CDD:223711	33/144 (23%)
Prosbeta4R2	NP_001259950.1	proteasome_beta_type_2	3..194	CDD:239727	32/143 (22%)
PRE5	NP_014045.1	Ntn_hydrolase	6..217	CDD:412394	33/144 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900