DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta4R2 and psmb2

DIOPT Version :9

Sequence 1:	NP_001259950.1	Gene:	Prosbeta4R2 / 33451	FlyBaseID:	FBgn0031443	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_001002609.1	Gene:	psmb2 / 436882	ZFINID:	ZDB-GENE-040718-353	Length:	199	Species:	Danio rerio

Alignment Length:	197	Identity:	89/197 - (45%)
Similarity:	134/197 - (68%)	Gaps:	0/197 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 METILGIKGPDFVMLASDTMQAKSLVFMKDDQSKIHRLSDFNMMATVGDGGDTIQFTDFISKNLH 67
            ||.::||:|||||::|:|.:.|.|::.||.|..|:.:||:..::..||:.|||:||.::|.||:.
Zfish     1 MEYLIGIQGPDFVLVAADNVAASSIIQMKHDYDKMFKLSEKILLLCVGEAGDTVQFAEYIQKNVQ 65

  Fly    68 LYKISHGYHLSAKSAAHFTRKTLADYIRTNTRYQVAMLLAGYDAVEGPDLHYIDSYGAAQSINHA 132
            |||:.:||.||..:||:||||.||||:|:.|.|.|.:||||||..:||.|:|:|...|......|
Zfish    66 LYKMRNGYELSPAAAANFTRKNLADYLRSRTPYHVNLLLAGYDETDGPGLYYMDYLSALAKAPFA 130

  Fly   133 GHGWGSMFCGSILQRYWNSKLSQEDAYSLMKKCVLEIQRRLIINQRNFEVYVVDSKGMRKMEAIN 197
            .||:|:....|||.||:...|::|:|..|:|||:.|:.:|.|:|..:|.|.::|..|:..||.:.
Zfish   131 AHGYGAFLTLSILDRYYRPDLTREEAVDLLKKCLEELNKRFILNLPSFTVRLIDKDGIHDMEKLP 195

  Fly   198 PG 199
            .|
Zfish   196 VG 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta4R2	NP_001259950.1	PRE1	1..194	CDD:223711	86/190 (45%)
Prosbeta4R2	NP_001259950.1	proteasome_beta_type_2	3..194	CDD:239727	86/190 (45%)
psmb2	NP_001002609.1	proteasome_beta_type_2	1..192	CDD:239727	86/190 (45%)
psmb2	NP_001002609.1	PRE1	5..188	CDD:223711	83/182 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580858
Domainoid	1	1.000	210	1.000	Domainoid score	I2770
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53714
OrthoDB	1	1.010	-	-		D1392180at2759
OrthoFinder	1	1.000	-	-		FOG0002770
OrthoInspector	1	1.000	-	-		otm26564
orthoMCL	1	0.900	-	-		OOG6_102061
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1860
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.720