DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta4R2 and Prosbeta4R1

DIOPT Version :9

Sequence 1:	NP_001259950.1	Gene:	Prosbeta4R2 / 33451	FlyBaseID:	FBgn0031443	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_608698.2	Gene:	Prosbeta4R1 / 33449	FlyBaseID:	FBgn0031442	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	205	Identity:	90/205 - (43%)
Similarity:	145/205 - (70%)	Gaps:	0/205 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 METILGIKGPDFVMLASDTMQAKSLVFMKDDQSKIHRLSDFNMMATVGDGGDTIQFTDFISKNLH 67
            ||||||:||.||::||||||:.||.:::.|:..|.||:||:.||:|.|||||.::|:|||.:|:.
  Fly     1 METILGVKGTDFIILASDTMRNKSAMWLDDEVRKTHRISDYCMMSTAGDGGDCLKFSDFILRNMD 65

  Fly    68 LYKISHGYHLSAKSAAHFTRKTLADYIRTNTRYQVAMLLAGYDAVEGPDLHYIDSYGAAQSINHA 132
            ||||::||.|:.:.|.||.|:.|:.|::::..:||::|:.|||...||:|||||..|.:..:.:.
  Fly    66 LYKITNGYDLTVRGAVHFIRRHLSAYLKSDCTFQVSLLVGGYDLTSGPELHYIDYLGNSVPVRYG 130

  Fly   133 GHGWGSMFCGSILQRYWNSKLSQEDAYSLMKKCVLEIQRRLIINQRNFEVYVVDSKGMRKMEAIN 197
            |||....||..||:.::...:..:.||.::||||:|:.:|.:||.||.:::::...|:.||.:||
  Fly   131 GHGAAMNFCTPILEEFYKPDMDTQAAYDVIKKCVIELYKRFVINLRNIDLFLISKNGITKMNSIN 195

  Fly   198 PGSLNKESIS 207
            ..||..:.::
  Fly   196 LESLRGDILA 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta4R2	NP_001259950.1	PRE1	1..194	CDD:223711	85/190 (45%)
Prosbeta4R2	NP_001259950.1	proteasome_beta_type_2	3..194	CDD:239727	85/190 (45%)
Prosbeta4R1	NP_608698.2	PRE1	1..204	CDD:223711	90/202 (45%)
Prosbeta4R1	NP_608698.2	proteasome_beta_type_2	1..193	CDD:239727	86/191 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449308
Domainoid	1	1.000	143	1.000	Domainoid score	I1496
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1634
Isobase	1	0.950	-	0	Normalized mean entropy	S587
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392180at2759
OrthoFinder	1	1.000	-	-		FOG0002770
OrthoInspector	1	1.000	-	-		mtm1116
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1860
	11	10.850