DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta4R2 and Psmb2

DIOPT Version :9

Sequence 1:	NP_001259950.1	Gene:	Prosbeta4R2 / 33451	FlyBaseID:	FBgn0031443	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_058980.1	Gene:	Psmb2 / 29675	RGDID:	61874	Length:	201	Species:	Rattus norvegicus

Alignment Length:	194	Identity:	88/194 - (45%)
Similarity:	132/194 - (68%)	Gaps:	0/194 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 METILGIKGPDFVMLASDTMQAKSLVFMKDDQSKIHRLSDFNMMATVGDGGDTIQFTDFISKNLH 67
            ||.::||:|||:|::|||.:.|.::|.||||..|:.::|:..::..||:.|||:||.::|.||:.
  Rat     1 MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQ 65

  Fly    68 LYKISHGYHLSAKSAAHFTRKTLADYIRTNTRYQVAMLLAGYDAVEGPDLHYIDSYGAAQSINHA 132
            |||:.:||.||..:||:|||:.|||.:|:.|.|.|.:||||||..|||.|:|:|...|......|
  Rat    66 LYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFA 130

  Fly   133 GHGWGSMFCGSILQRYWNSKLSQEDAYSLMKKCVLEIQRRLIINQRNFEVYVVDSKGMRKMEAI 196
            .||:|:....|||.||:...:|:|.|..|::||:.|:|:|.|:|...|.|.|:|..|:..:|.|
  Rat   131 AHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRVIDKDGIHNLENI 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta4R2	NP_001259950.1	PRE1	1..194	CDD:223711	86/190 (45%)
Prosbeta4R2	NP_001259950.1	proteasome_beta_type_2	3..194	CDD:239727	86/190 (45%)
Psmb2	NP_058980.1	proteasome_beta_type_2	1..192	CDD:239727	86/190 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340975
Domainoid	1	1.000	200	1.000	Domainoid score	I2943
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3471
OMA	1	1.010	-	-		QHG53714
OrthoDB	1	1.010	-	-		D1392180at2759
OrthoFinder	1	1.000	-	-		FOG0002770
OrthoInspector	1	1.000	-	-		otm45001
orthoMCL	1	0.900	-	-		OOG6_102061
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1860
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770