DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta4R2 and Psma4

DIOPT Version :9

Sequence 1:	NP_001259950.1	Gene:	Prosbeta4R2 / 33451	FlyBaseID:	FBgn0031443	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_058977.1	Gene:	Psma4 / 29671	RGDID:	61846	Length:	261	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	41/186 - (22%)
Similarity:	72/186 - (38%)	Gaps:	37/186 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AME------TILGIKGPDFVMLASDTMQAKSL---VFMKDDQSKIHRLSDFNMMATVGDGGDTIQ 57
            |||      |.|||...|.|:||::......|   ||..:   ||::|::....:..|...|...
  Rat    24 AMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSE---KIYKLNEDMACSVAGITSDANV 85

  Fly    58 FTDFISKNLHLYKISHGYHLSAKSAAHFTRKTLADYIRTNTR------YQVAMLLAGYDAVEGPD 116
            .|:.:......|.:.:...:..:...    ..|.|..:..|:      :.|::|..|:|...|..
  Rat    86 LTNELRLIAQRYLLQYQEPIPCEQLV----TALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQ 146

  Fly   117 LHYIDSYGAAQSINHAGHGWGSMFCGS--------ILQRYWNSKLSQEDAYSLMKK 164
            |:..|..|     |:.  ||.:...|:        :.|.|...:::.:.|.:|..|
  Rat   147 LYQSDPSG-----NYG--GWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAVK 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta4R2	NP_001259950.1	PRE1	1..194	CDD:223711	41/186 (22%)
Prosbeta4R2	NP_001259950.1	proteasome_beta_type_2	3..194	CDD:239727	40/185 (22%)
Psma4	NP_058977.1	proteasome_alpha_type_4	3..216	CDD:239721	41/186 (22%)
Psma4	NP_058977.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..261
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900