DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9962 and YCK3

DIOPT Version :9

Sequence 1:	NP_608697.1	Gene:	CG9962 / 33448	FlyBaseID:	FBgn0031441	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_011049.2	Gene:	YCK3 / 856860	SGDID:	S000000925	Length:	524	Species:	Saccharomyces cerevisiae

Alignment Length:	335	Identity:	126/335 - (37%)
Similarity:	182/335 - (54%)	Gaps:	63/335 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KLGSGSFGDIYEAKHMGSGLH--------------------VALKVERKNAGQSHLSIESTVYNL 64
            |:|.||||.|:|.:::   ||                    ||:|.|.:::....|..|...|.:
Yeast    19 KIGEGSFGVIFEGENI---LHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRI 80

  Fly    65 LRHGMGIPMTYQFFSNRRHDVLVMELLGPSLETLFTMCNRRFSMKTVLMLADQMVDRLEYLHLHH 129
            |...:|||..|.|.....|::|:::|||||||.||..|.|:||:||..|:|.||:||:..:|.|.
Yeast    81 LNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHD 145

  Fly   130 YVHRDIKPENFLMGVGLTRHR----------------------LHLIDFGLSKRYWDMKENRHVP 172
            .::|||||:|||    :::::                      ::::|||::|:|.|.:..:|:|
Yeast   146 LIYRDIKPDNFL----ISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIP 206

  Fly   173 QRRGTKWAGTARYASVNALCCKVQSRRDDLESVGYVLIYLLRGSLPWQGL-LPNSKLQKAEMILE 236
            .|.....:|||||.|:|....:.|||||||||:|:|..|.|||||||||| .||:|| |.|.|..
Yeast   207 YRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKL-KYEKIGM 270

  Fly   237 MKLSTLPNSLCA--GYPNEFYNYIIYTRQLGFEEEPDYRMIRCTFLSLLFNLKFTNDL----IYD 295
            .|....|:.|..  ..|.:|..|:.|.|.|.|:|:|||..:    :||:.:....|||    .||
Yeast   271 TKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYL----ISLMDDALRLNDLKDDGHYD 331

  Fly   296 WDHAEKNSGK 305
            |  .:.|.||
Yeast   332 W--MDLNGGK 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9962	NP_608697.1	SPS1	16..>259	CDD:223589	107/283 (38%)
CG9962	NP_608697.1	STKc_CK1	17..279	CDD:270918	115/303 (38%)
YCK3	NP_011049.2	PKc_like	13..320	CDD:419665	117/312 (38%)
YCK3	NP_011049.2	ROM1	361..>479	CDD:227709
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770