DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9962 and vrk3

DIOPT Version :9

Sequence 1:	NP_608697.1	Gene:	CG9962 / 33448	FlyBaseID:	FBgn0031441	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001013586.1	Gene:	vrk3 / 541443	ZFINID:	ZDB-GENE-030131-246	Length:	459	Species:	Danio rerio

Alignment Length:	288	Identity:	81/288 - (28%)
Similarity:	127/288 - (44%)	Gaps:	52/288 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ELETMLRINSIMVIRKLGSGSFGDIYEAKHMGSGLHVALKVERKNA----GQSH----LSIESTV 61
            |.:.|||:.:     |.|           |:.:..:..|:..:.:|    |:.|    |.|.|.|
Zfish   193 ECKYMLRLGA-----KEG-----------HLFNEQNFHLRAAKPDAVEKWGKLHKLDFLGIPSCV 241

  Fly    62 YNLLRHGMGIPMTYQFFSNRRHDVLVMELLGPSLETLFTMCNRRFSMKTVLMLADQMVDRLEYLH 126
                  |.|:..||:|        ||...:|..|:|.........|.|.||.||.:::|.||::|
Zfish   242 ------GFGLHETYRF--------LVFPCMGQPLQTELDEGTGSLSEKNVLQLALRLLDSLEFIH 292

  Fly   127 LHHYVHRDIKPENFLMGVGLTRH-RLHLIDFGLSKRYWDMKENRHVPQRRGTKWA--GTARYASV 188
            ...|.|.||...|..  :..:.| .:.|..||.:.|:  ....:||..|:|::.|  |...:.|:
Zfish   293 EKEYAHADIHAGNIY--IKSSSHTEVFLSGFGHAFRF--CPGGKHVEYRQGSRTAHQGNISFISL 353

  Fly   189 NALCCKVQSRRDDLESVGYVLIYLLRGSLPWQGLLPNSKLQKAEMILEMKLSTLPNSLCAGYPNE 253
            ::......|||.||:|:||.::..:.|||||..|..||....||.  |..:|.:|..|...|..:
Zfish   354 DSHKGAGPSRRSDLQSLGYCMLCWMTGSLPWSHLSHNSSSVAAEK--ERYMSDVPGLLTYCYKQK 416

  Fly   254 -----FYNYIIYTRQLGFEEEPDYRMIR 276
                 ...|:.....|.:.|:|||.:::
Zfish   417 KASSALQEYLCNVMALQYTEKPDYTLLK 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9962	NP_608697.1	SPS1	16..>259	CDD:223589	72/258 (28%)
CG9962	NP_608697.1	STKc_CK1	17..279	CDD:270918	77/276 (28%)
vrk3	NP_001013586.1	DUF4758	<9..>104	CDD:292572
		PK_VRK3	154..451	CDD:271026	81/288 (28%)
		SPS1	236..>384	CDD:223589	51/165 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740