Protein Alignment Drp1 and rdcA

DIOPT Version :10

• Sequence 1: NP_608694.2
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_418533.1
• Gene: rdcA / 948620
• ECOCYCID: EG11210
• Length: 742
• Species: Escherichia coli
• Alignment Length: 658
• Identity: 120/658 - (18%)
• Similarity: 220/658 - (33%)
• Gaps: 234/658 - (35%)

  Fly    28 IVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQ---------LIYS---PLD------- 73
            :.::|:..:|||:.|.::||...||.....:|..|.:::         |.:|   |:|
E. coli    72 LAIVGTMKAGKSTTINAIVGTEVLPNRNRPMTALPTLIRHTPGQKEPVLHFSHVAPIDCLIQQLQ 136

  Fly    74 -----------------DRENRSAENGTSNAEEWGRF-------LHTKKCFTDFDEIRKEIENET 114
                             |::.|:......|...:.::       .|..|...|...:.|.::.:.
E. coli   137 QRLRDCDIKHLTDVLEIDKDMRALMQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDF 201

  Fly   115 ERAAGSNKGICP----EPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIEN 175
            ..:|.:.....|    |.::|....::...|||:|.||..:   ..||     .:::::.:.:..
E. coli   202 PFSAYAAIEHIPVIEVEFVHLAGLESYPGQLTLLDTPGPNE---AGQP-----HLQKMLNQQLAR 258

  Fly   176 PNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAV---------VTKLDLMDAGTDAID---- 227
            .::::..:........:.|.::.|         .|||         |.|.|..|..:|..|
E. coli   259 ASAVLAVLDYTQLKSISDEEVREA---------ILAVGQSVPLYVLVNKFDQQDRNSDDADQVRA 314

  Fly   228 -----ILCGRVIPVKLGIIGVM-----NRSQ--------------------------------KD 250
                 ::.|.:.|.::..:..|     ||::                                .|
E. coli   315 LISGTLMKGCITPQQIFPVSSMWGYLANRARYELANNGKLPPPEQQRWVEDFAHAALGRRWRHAD 379

  Fly   251 IMDQKHI---DDQMKDEAAFLQRKYPTL--ATRNGTPY-LAKTLNRLL----------------- 292
            :.|.:||   .||:.:::.|.|.....|  |..|.:.| |....::||
E. coli   380 LADLEHIRHAADQLWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGL 444

  Fly   293 ----------MHHIRDCLP-----------DLKTRVNIMATQFQSLLNSYGEDV--------SDK 328
                      :|.|.:.|.           ::|..:.:..|.....|....:.:        .|.
E. coli   445 NVACEQLRQNIHQIEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDALKVQLAALFQDD 509

  Fly   329 SQTLLQIITKFSSAYCCTIEGTARN------------IETTELCGGARMGYIFHETFGRTL-DSI 380
            |:.|.:|.|:     |.|:..||:|            :|:| ||              |.| |.|
E. coli   510 SEPLSEIRTR-----CETLLQTAQNTISRDFTLRFAELEST-LC--------------RVLTDVI 554

  Fly   381 HPLAGLSKMDILTAIRNATGPRPAL-------FVPEVSFELLVKRQIRRLE---EPSLRCVELIH 435
            .|:....||::     :.:|.||..       .||..:...|....|.|.|   |.|.| :.::.
E. coli   555 RPIEQQVKMEL-----SESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTR-LGVVR 613

  Fly   436 EEMQRIVQH----CGNEVQ-QEMLRFPKLHEKI---VDVVTQLLRRRLPHTNVMVENIVAIELAY 492
            |...|.:..    .|||.. .|.:.:..|...:   ||:..|.:.:      |:.|.:.....|.
E. coli   614 ETFSRWLNQPDWGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAK------VLAEQVDESVTAG 672

  Fly   493 INTKHPDF 500
            :||...:|
E. coli   673 MNTFFAEF 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_608694.2	DLP_1	23..301	CDD:206738	67/407 (16%)
		Dynamin_M	224..507	CDD:460033	77/406 (19%)
		GED	639..729	CDD:460495
rdcA	NP_418533.1	PRK09866	1..741	CDD:182123	120/658 (18%)