DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drp1 and DRP4A

DIOPT Version :9

Sequence 1:	NP_001259946.1	Gene:	Drp1 / 33445	FlyBaseID:	FBgn0026479	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	NP_176253.1	Gene:	DRP4A / 842348	AraportID:	AT1G60530	Length:	301	Species:	Arabidopsis thaliana

Alignment Length:	281	Identity:	107/281 - (38%)
Similarity:	160/281 - (56%)	Gaps:	32/281 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLI 68
            |:..:::|:::  .|..:.||||.|||:|.||||||||:||:.|.: ||||.||.||.|||::|
plant    43 LLDTVDRLRNL--NVMREGIQLPTIVVVGDQSSGKSSVLESLAGIN-LPRGQGICTRVPLVMRL- 103

  Fly    69 YSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDEIRKEIENETERAAGSNKGICPEPINLKI 133
                    .||:   :...|.|..: ..|...||.:.:.:.|...|:..||:.:|:...|:.|.:
plant   104 --------QRSS---SPEPEIWLEY-SDKVVPTDEEHVAEAICAATDVIAGTGEGVSDTPLTLSV 156

  Fly   134 FSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKL 198
            ...:|.:||:|||||||:|||..|||:|..||..:::||||...||||.|.:|..|..|.|::::
plant   157 KKNNVPDLTMVDLPGITRVPVNGQPENIYEQISRMIMKYIEPQESIILNVLSATVDFTTCESIRM 221

  Fly   199 AKDVDPDGRRTLAVVTKLDLMDAG----TDAIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHIDD 259
            ::.||..|.||||||||.|:...|    ..|.|:..|      ||.|.|.||..::..::..:.:
plant   222 SRQVDKTGERTLAVVTKADMAPEGLLQKVTADDVSIG------LGYICVRNRIGEETYEEARVQE 280

  Fly   260 QMKDEAAFLQRKYPTLATRNG 280
            .:      |.|.:|.|:..:|
plant   281 DL------LFRTHPLLSLIDG 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_001259946.1	DLP_1	23..301	CDD:206738	104/262 (40%)
		CrfC	88..728	CDD:223771	71/197 (36%)
		Dynamin_M	226..507	CDD:279383	13/55 (24%)
		GED	643..729	CDD:280391
DRP4A	NP_176253.1	DLP_1	60..300	CDD:206738	104/262 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810