Protein Alignment Drp1 and DRP4C

DIOPT Version :10

• Sequence 1: NP_608694.2
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_176252.1
• Gene: DRP4C / 842345
• AraportID: AT1G60500
• Length: 669
• Species: Arabidopsis thaliana
• Alignment Length: 785
• Identity: 197/785 - (25%)
• Similarity: 332/785 - (42%)
• Gaps: 225/785 - (28%)

  Fly     4 LIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLI 68
            |:..:::|:::  .|..:.|.||.|||:|.||||||||:||:.|.| ||||.||.||.|||::|
plant    46 LLDTVDRLRNL--NVMREGIHLPTIVVVGDQSSGKSSVLESLAGIS-LPRGQGICTRVPLVMRL- 106

  Fly    69 YSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDEIRKEIENETERAAGSNKGICPEPINLKI 133
                    .||:   :...|.|..: :.|...||.:.|.:.|...|:..|||.||:...|:.|.:
plant   107 --------QRSS---SPEPEIWLEY-NDKVVPTDEEHIAEAIRAATDVIAGSGKGVSDAPLTLHV 159

  Fly   134 FSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKL 198
            ....|.:||:|||||||:|||..|||:|..||..::::|||...||||.|.:|..|..|.|::::
plant   160 KKAGVPDLTMVDLPGITRVPVNGQPENIYEQISGMIMEYIEPQESIILNVLSATVDFTTCESIRM 224

  Fly   199 AKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRV----IPVKLGIIGVMNRSQKDIMDQKHIDD 259
            ::.||..|:||||||||.|:...|      |..:|    :.:.||.:.|.||    |.::.:.:.
plant   225 SRKVDKTGQRTLAVVTKADMAPEG------LLQKVTADDVSIVLGYVCVRNR----IGEETYEEA 279

  Fly   260 QMKDEAAFLQRKYPTLATRN----GTPYLAKTLNRLLMHHIRDCLPDLKTRVN------------ 308
            :|::|..|  |.:|.|:..:    |.|.||:.|..:....|..|||.:.:::|
plant   280 RMQEELLF--RTHPVLSLIDEDIVGIPVLAQKLMLIQSSMIARCLPKIVSKINQKLDTAVLELNK 342

  Fly   309 ---IMATQFQSLLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFH 370
               :||:..::|: :..:.:....::||:|:          ::|
plant   343 LPMVMASTGEALM-ALMDIIGSAKESLLRIL----------VQG--------------------- 375

  Fly   371 ETFGRTLD--SIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVEL 433
             .|....|  ::|..|.|:  |:|:...::...:|    .||: |.|:. :|:.|:|  .:||.|
plant   376 -DFSEYPDDQNMHCTARLA--DMLSQFSDSLQAKP----KEVA-EFLMD-EIKILDE--CKCVGL 429

  Fly   434 IH-----EEMQRIVQHCGNEVQQEMLRF-PKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAY 492
            .:     ..:..:.||. :.:|.:.:.| .|:.:.|.||::.:..:|
plant   430 PNFIPRSAFLAILSQHV-DGIQDKPVEFINKIWDYIEDVLSSVTAKR------------------ 475

  Fly   493 INTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQP 557
                                  ||.:.||....:||.  ||.:
plant   476 ----------------------SDNFPQIQSSIKRAG--RNLI---------------------- 494

  Fly   558 NSSQQQYSQVHEQ--NHVAENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPV 620
                   |::.||  |.|.|.......:.:..|        |:.:.:.|..|....:.:..|...
plant   495 -------SKIKEQSVNRVMEIVEMEKLTDYTCN--------PEYMTSWTQKTSAQESFIDAVVKN 544

  Fly   621 NLLPD-----------------------VPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQ 662
            ..:||                       :||.....|:|               ||:.||.:.|.
plant   545 ENIPDYFSVTGFGNVKISHLRKYHAHLLIPAFDMKMRIT---------------SYWKIVLRRIV 594

  Fly   663 DSVPKAIMHFLVNYVKDNLQSELVTHLY---KSDKAETLLNESDHIAVRRKEAADMLKALTRANH 724
            |::...:...:.:.|....|.|:|..:.   .....|.:|.||..:|.:|::..:.:|.|..:..
plant   595 DNLALYLQLSVKSLVNTRFQKEIVAEMVDPRDGGGVEKMLEESPLVASKREKLQNSIKLLKESKD 659

  Fly   725 IISEI 729
            .::.|
plant   660 AVAAI 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_608694.2	DLP_1	23..301	CDD:206738	113/285 (40%)
		Dynamin_M	224..507	CDD:460033	58/313 (19%)
		GED	639..729	CDD:460495	18/92 (20%)
DRP4C	NP_176252.1	DLP_1	63..323	CDD:206738	113/285 (40%)
		Dynamin_M	248..529	CDD:460033	75/415 (18%)
		GED	567..664	CDD:128597	22/111 (20%)