Protein Alignment Drp1 and DL3

DIOPT Version :10

• Sequence 1: NP_608694.2
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_176170.1
• Gene: DL3 / 842251
• AraportID: AT1G59610
• Length: 920
• Species: Arabidopsis thaliana
• Alignment Length: 905
• Identity: 175/905 - (19%)
• Similarity: 323/905 - (35%)
• Gaps: 269/905 - (29%)

  Fly     1 MEALIPVINKLQDVFNTVGS----------DSIQLP----QIVVLGSQSSGKSSVIESVVGRSFL 51
            ||| |..:::|.|......|          .|.:.|    .:|.||:..:|||:|:.|::|...|
plant     1 MEA-IDELSQLSDSMRQAASLLADEDPDETSSSRRPATSLNVVALGNVGAGKSAVLNSLIGHPVL 64

  Fly    52 PRGTGIVTRRPLVLQLIYSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDE---------IR 107
            |.|....||.|:::.|      .||..               |.:|......|.         :|
plant    65 PTGENGATRAPIIIDL------SREES---------------LSSKAIILQIDNKNQQVSASALR 108

  Fly   108 KEIENETERAAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKY 172
            ..:::...:.| |.:|  .:.|.||:.::....|.|:||||:.:..|.|          .::.::
plant   109 HSLQDRLSKGA-SGRG--RDEIYLKLRTSTAPPLKLIDLPGLDQRIVDD----------SMIGEH 160

  Fly   173 IENPNSIILAVTAAN--TDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTD-----AIDILC 230
            .::.::|:|.|..|:  :::::|.|||:||:.||:..||:.:::|:|  .|..:     |:..|.
plant   161 AQHNDAILLVVVPASQASEISSSRALKIAKEYDPESTRTVGIISKID--QAAENPKSLAAVQALL 223

  Fly   231 GRVIPVK------LGIIG--VMNRSQKDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKT 287
            ....|.|      :.:||  |...|.:....:..::...:.|:..|:      :...|.|  ...
plant   224 SNQGPPKTTDIPWVALIGQSVSIASAQSGGSENSLETAWRAESESLK------SILTGAP--QSK 280

  Fly   288 LNRLLMHHIRDCLPDLKTRVNIMATQFQS----LLNSYGEDVSDKSQTLLQIITKFSSAYCCTIE 348
            |.|:.:             |:.:|:|.:|    .|.:....:..|||.:...:.:.......:.|
plant   281 LGRIAL-------------VDTLASQIRSRMKLRLPNILTGLQGKSQIVQDELARLGEQLVSSAE 332

  Fly   349 GTARNIETTELC------------GGARMGY----IFHETFGRTLDSIHPLAGLSKMDILTAIRN 397
            || |.| ..|||            ||...|:    .|...|...:..:.........::...:..
plant   333 GT-RAI-ALELCREFEDKFLLHLAGGEGSGWKVVASFEGNFPNRIKKLPLDRHFDLNNVKRIVLE 395

  Fly   398 ATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEK 462
            |.|.:|.|..||.....|:|..:...::|:..||:.:|..:..||....| ....:.|:|....:
plant   396 ADGYQPYLISPEKGLRSLIKTVLELAKDPARLCVDEVHRVLVDIVSASAN-ATPGLGRYPPFKRE 459

  Fly   463 IVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRR 527
            :|.:.:..|.........||..:|.:|.|::..:|                      .|.|.|||
plant   460 VVAIASAALDGFKNEAKKMVVALVDMERAFVPPQH----------------------FIRLVQRR 502

  Fly   528 ANTPRNHMSPQISSHSAGSQQPQQQ---------QPPQPNS------SQQQYSQVHEQNHVAENS 577
            ..  |.....::...|:...|..:|         ||..|:|      |.:......:::...|..
plant   503 ME--RQRREEELKGRSSKKGQDAEQSLLNRATSPQPDGPSSTGGSLKSLRDKLMPQDKDKDKEKE 565

  Fly   578 TPSMAS---------------------------TW------------------------------ 585
            ||.::.                           .|
plant   566 TPEVSGLKTAGPEGEITAGYLMKKSAKTNGWSRRWFVLNEKTGKLGYTKKQEERNFRGTVTLEEC 630

  Fly   586 -LSNILPPAPTRPDSIENSTNNTP----------------------VHNNIVSPVKP-------V 620
             :..|......:..|.::..:|.|                      .||.:|...:.       :
plant   631 SIEEISDDEGEKSKSSKDKKSNGPDSKGPGLVFKITCRVPYKTVLKAHNALVLKAESMVDKNEWI 695

  Fly   621 NLLPDV-------PANHNPRR------LTDKEQKDCDVIEHL------IKSYFYIVRKSIQDSVP 666
            |.|..|       ..:.:.|:      |....:|..|..|.|      ::.|...|..|:..:||
plant   696 NKLQKVIQARGGQVGSASMRQSLSEGSLDKMVRKPVDPEEELRWMSQEVRGYVEAVLNSLAANVP 760

  Fly   667 KAIMHFLVNYVKDNLQSELVTHL--YKSDKAETLLNESDHIAVRR---KEAADMLKALTR 721
            ||::...|...|:::.::|.:.:  ..:::.|:|:.|..::..||   ::.:.:|..|||
plant   761 KAVVLCQVEKSKEDMLNQLYSSISAIGNERIESLIQEDQNVKRRRDRYQKQSSLLSKLTR 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_608694.2	DLP_1	23..301	CDD:206738	68/305 (22%)
		Dynamin_M	224..507	CDD:460033	60/315 (19%)
		GED	639..729	CDD:460495	23/94 (24%)
DL3	NP_176170.1	DLP_1	41..303	CDD:206738	71/318 (22%)
		Dynamin_M	<286..494	CDD:460033	45/223 (20%)
		PH	584..703	CDD:214574	11/118 (9%)
		GED	744..817	CDD:470615	16/72 (22%)