Protein Alignment Drp1 and ADL6

DIOPT Version :10

• Sequence 1: NP_608694.2
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_172500.1
• Gene: ADL6 / 837568
• AraportID: AT1G10290
• Length: 914
• Species: Arabidopsis thaliana
• Alignment Length: 893
• Identity: 179/893 - (20%)
• Similarity: 319/893 - (35%)
• Gaps: 252/893 - (28%)

  Fly     1 MEALIPVINKLQDVFNTVGS----------DSIQLP----QIVVLGSQSSGKSSVIESVVGRSFL 51
            ||| |..:::|.|......|          .|.:.|    .:|.||:..:|||:|:.|::|...|
plant     1 MEA-IDELSQLSDSMKQAASLLADEDPDETSSSKRPATFLNVVALGNVGAGKSAVLNSLIGHPVL 64

  Fly    52 PRGTGIVTRRPLVLQLI-YSPLDDR------ENRSAENGTSNAEEWGRFLHTKKCFTDFDEIRKE 109
            |.|....||.|::::|. .|.|..:      :|:|.:...|                   .:|..
plant    65 PTGENGATRAPIIIELSRESSLSSKAIILQIDNKSQQVSAS-------------------ALRHS 110

  Fly   110 IENETER-AAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYI 173
            :::...: |:|.|:    :.||||:.::....|.||||||:      ||....|:.|.|    |.
plant   111 LQDRLSKGASGKNR----DEINLKLRTSTAPPLKLVDLPGL------DQRIVDESMIAE----YA 161

  Fly   174 ENPNSIILAVTAAN--TDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTD---AIDILCGRV 233
            ::.::|:|.:..|:  :::::|.|||:||:.||:..||:.::.|:|.....:.   |:..|....
plant   162 QHNDAILLVIVPASQASEISSSRALKIAKEYDPESTRTIGIIGKIDQAAENSKALAAVQALLSNQ 226

  Fly   234 IPVK------LGIIG--VMNRSQKDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKTLNR 290
            .|.|      :.:||  |...|.:....:..::...:.|:..|:      :...|.|  ...|.|
plant   227 GPPKTTDIPWVAVIGQSVSIASAQSGSGENSLETAWRAESESLK------SILTGAP--QSKLGR 283

  Fly   291 LLMHHIRDCLPDLKTRVNIMATQFQS----LLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTA 351
            :.:             |:.:|:|.:|    .|.|....:..|||.:...:.:.......:.|||
plant   284 IAL-------------VDTLASQIRSRMKLRLPSVLSGLQGKSQIVQDELARLGEQLVNSAEGT- 334

  Fly   352 RNIETTELC------------GGARMGY----IFHETFGRTLDSIHPLAGLSKMDILTAIRNATG 400
            |.| ..|||            ||...|:    .|...|...:..:.........::...:..|.|
plant   335 RAI-ALELCREFEDKFLLHLAGGEGSGWKVVASFEGNFPNRIKQLPLDRHFDLNNVKRVVLEADG 398

  Fly   401 PRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVD 465
            .:|.|..||.....|:|..:...::|:..||:.:|..:..||....| ....:.|:|....::|.
plant   399 YQPYLISPEKGLRSLIKIVLELAKDPARLCVDEVHRVLVDIVSASAN-ATPGLGRYPPFKREVVA 462

  Fly   466 VVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANT 530
            :.:..|.........||..:|.:|.|::..:|                      .|.|.|||...
plant   463 IASAALDGFKNEAKKMVVALVDMERAFVPPQH----------------------FIRLVQRRMER 505

  Fly   531 PRNH----------------------MSPQISSHSAGSQQPQQQQPPQPNSSQQQ---------- 563
            .|..                      .|||....:||......:..|.|...:..
plant   506 QRREEELKGRSSKKGQDAEQSLLSRATSPQPDGPTAGGSLKSMKDKPSPQDKETPEVSGLKTAGP 570

  Fly   564 ----------------------------------YSQVHEQNH--------------VAENSTPS 580
                                              |::..|:.:              :.|:....
plant   571 EGEITAGYLMKKSAKTNGWSRRWFVLNEKTGKLGYTKKQEERNFRGTITLEECTIEEIPEDEVEK 635

  Fly   581 MASTWLSNILPPAPTRPDSIENSTNNTP------VHNNIVSPVKPV-------NLLPDV------ 626
            ..|:.......|....|..:...|...|      .||.:|...:.|       |.|..|
plant   636 SKSSKDKKANGPDSKGPGLVFKITCKVPYKTVLKAHNALVLKAESVVDKNEWINKLQKVIQARGG 700

  Fly   627 -------PANHNPRRLTDKEQKDCDVIEHL------IKSYFYIVRKSIQDSVPKAIMHFLVNYVK 678
                   ..:.:...|....:|..|..|.|      ::.|...|..|:..:||||::...|...|
plant   701 QVGSVSMRQSLSEGSLDKMVRKPIDPEEELRWMSQEVRGYVEAVLNSLAANVPKAVVLCQVEKAK 765

  Fly   679 DNLQSELVTHL--YKSDKAETLLNESDHIAVRR---KEAADMLKALTR 721
            :::.::|.:.:  ..:::.|:|:.|..::..||   ::.:.:|..|||
plant   766 EDMLNQLYSSISAIGNERIESLIQEDQNVKRRRERYQKQSSLLSKLTR 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_608694.2	DLP_1	23..301	CDD:206738	72/302 (24%)
		Dynamin_M	224..507	CDD:460033	61/313 (19%)
		GED	639..729	CDD:460495	23/94 (24%)
ADL6	NP_172500.1	DLP_1	41..303	CDD:206738	75/315 (24%)
		Dynamin_M	<286..494	CDD:460033	46/223 (21%)
		PH	577..696	CDD:214574	15/118 (13%)
		GED	737..810	CDD:470615	16/72 (22%)