Protein Alignment Drp1 and si:dkey-32e23.4

DIOPT Version :10

• Sequence 1: NP_608694.2
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: XP_073767341.1
• Gene: si:dkey-32e23.4 / 566871
• ZFINID: ZDB-GENE-081105-41
• Length: 706
• Species: Danio rerio
• Alignment Length: 748
• Identity: 448/748 - (59%)
• Similarity: 548/748 - (73%)
• Gaps: 90/748 - (12%)

  Fly     1 MEALIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVL 65
            ||.|||:||:||:||.|||::.||||||||:||||||||||:||:|||.|||||:||||||||||
Zfish    36 METLIPIINRLQEVFLTVGAEIIQLPQIVVVGSQSSGKSSVLESLVGRDFLPRGSGIVTRRPLVL 100

  Fly    66 QLI-YSPLDDRE-----NRSAENGTSN-----AEEWGRFLHTK-KCFTDFDEIRKEIENETERAA 118
            ||: ..||::|.     |.|.:|..:|     |||||.|||.| :.||||:|||||||.||:|:.
Zfish   101 QLVNVPPLEERRKQDNGNGSKQNSQNNYPGIKAEEWGTFLHCKNQIFTDFNEIRKEIEEETDRST 165

  Fly   119 GSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAV 183
             :||||..|||.|||:|.:|::||||||||||||||||||||||.|::|::|.||.||||:||.|
Zfish   166 -NNKGISKEPIYLKIYSPNVLSLTLVDLPGITKVPVGDQPEDIEIQVQEMILSYISNPNSLILCV 229

  Fly   184 TAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVMNRSQ 248
            :.||:|:|||:|||||::||.||||||.||:|||||||||||:::|.||||||:||||||:||||
Zfish   230 SPANSDLATSDALKLAREVDADGRRTLLVVSKLDLMDAGTDALEVLLGRVIPVRLGIIGVVNRSQ 294

  Fly   249 KDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKTLNRLLMHHIRDCLPDLKTRVNIMATQ 313
            .|:..||.:.|..:||.|||||.||:||:|.|:.|||:||:||||||||||||:|||||.::..|
Zfish   295 HDLNTQKSLSDSCRDEQAFLQRHYPSLASRCGSRYLARTLSRLLMHHIRDCLPELKTRVTVLTAQ 359

  Fly   314 FQSLLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLD 378
            :||.|||||:.|.|.|.|||||:|||::.||.|||||||:|:|:||||||||.|||||||||||.
Zfish   360 YQSRLNSYGQPVEDHSATLLQIVTKFATDYCSTIEGTARHIQTSELCGGARMCYIFHETFGRTLQ 424

  Fly   379 SIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQ 443
            ||.||.||:::||||||||||||||||||||||||||||:||:||||||||||||:|||:|||:|
Zfish   425 SIDPLGGLTELDILTAIRNATGPRPALFVPEVSFELLVKKQIKRLEEPSLRCVELVHEELQRIIQ 489

  Fly   444 HCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVP 508
            ||.:...||:|||||||:.||:|||.|||:|||.||.||.|:||||||||||||||| .|||.|.
Zfish   490 HCSSYSTQELLRFPKLHDSIVEVVTGLLRKRLPITNEMVHNLVAIELAYINTKHPDF-TDAAQVS 553

  Fly   509 SLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQPNSSQQQYSQVHEQNHV 573
            :  ..:|......:.|:|..|                .:.|.:::.|.|...
Zfish   554 A--SVNSQQAEAGDGGKRWKN----------------EKMPSEEKGPMPGFG------------- 587

  Fly   574 AENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPVNLLPD-VPANHNPRRLTD 637
                                                     ||.|.:|||.. ||.:   |:|:.
Zfish   588 -----------------------------------------SPSKAINLLDTAVPVS---RKLSS 608

  Fly   638 KEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNES 702
            :||:||:||:.|||.||.||||||||||||.:||||||:||::||||||..|||....:.||.||
Zfish   609 REQRDCEVIQRLIKCYFLIVRKSIQDSVPKTVMHFLVNFVKEHLQSELVGQLYKQPLLQELLIES 673

  Fly   703 DHIAVRRKEAADMLKALTRANHIISEIRETHMW 735
            ...|.:|.|.|.||:||.:|::|||||||||:|
Zfish   674 QETAQQRTEVAHMLEALKKASNIISEIRETHLW 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_608694.2	DLP_1	23..301	CDD:206738	197/289 (68%)
		Dynamin_M	224..507	CDD:460033	207/282 (73%)
		GED	639..729	CDD:460495	56/89 (63%)
si:dkey-32e23.4	XP_073767341.1	None