Protein Alignment Drp1 and fzo

DIOPT Version :9

• Sequence 1: NP_001259946.1
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_732840.1
• Gene: fzo / 42745
• FlyBaseID: FBgn0011596
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 708
• Identity: 122/708 - (17%)
• Similarity: 220/708 - (31%)
• Gaps: 254/708 - (35%)

  Fly     1 MEALIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVL 65
            :|.|....::::.:...:..|.:   ::...|..|:|||:||.:::....||...|
  Fly    65 LEHLCAFSSRVEAIAKVLSRDRM---KVAFFGRTSNGKSAVINALLHEKILPSAMG--------- 117

  Fly    66 QLIYSPLDDRENRSAENGTSNAEEWGRFLHTKKCF--------TDFDEIRKEIENE-TERAAGSN 121
                                         ||..||        .:.:.::.|.|:| .|.:|.|.
  Fly   118 -----------------------------HTTSCFCQVQANGSNETEHVKVEQEDEHMELSALSQ 153

  Fly   122 KGICPEPINLKIFSTHVVNL------------TLVDLPGITKVPVGDQPEDIEAQIKELVLKYIE 174
            ......|..||..:...||:            .|:|.||:          |:.||:.:.:..|..
  Fly   154 LASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGV----------DVTAQLDDCLDSYCM 208

  Fly   175 NPNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLG 239
            :.:..||.:.|.:|  .:....:..||          |.:||.                   :..
  Fly   209 DADVFILVLNAEST--VSRVERQFFKD----------VASKLS-------------------RPN 242

  Fly   240 IIGVMNRSQKDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKTLNRLLMH-------HIR 297
            :..:.||..|....:..::.::||:  .::|....|....|....|:.....:.|       |||
  Fly   243 LFILNNRWDKASSLEPEMEQKVKDQ--HMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIR 305

  Fly   298 DCLPDLKTRVNIMATQFQSLLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGG 362
            :                ..:.|..|: ...:.|..|:....||:  |..:..    ::|
  Fly   306 N----------------GQITNPSGQ-TQQRYQEFLRFENDFSN--CLAVSA----LKT------ 341

  Fly   363 ARMGYIFHETFGRTLDSIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPS 427
                     .||..|        ||...||..:::      .|..|      .:::..|.::|..
  Fly   342 ---------KFGPHL--------LSAQKILNQLKS------TLICP------FIEKVSRLIDENK 377

  Fly   428 LRCVEL---------IHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVE 483
            .|...|         :.:|.:..:|:|..|:.:...|..:.      |:...::..:|.:
  Fly   378 ERRANLNAEIEDWLILMQEDREALQYCFEELTEMTQRVGRC------VLNDQIKTLIPSS----- 431

  Fly   484 NIVAIELAYINTKHPDF-------------HKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHM 535
                 .|::....||:|             |.|..|...:|:..|.|.      ||:.......:
  Fly   432 -----VLSFSQPFHPEFPAQIGQYQRSLCAHLDKLLEDRVLQCLSIPL------QRKILDIEKEI 485

  Fly   536 SPQISSHSA------GSQQPQQQQPPQPNSSQQQYSQVHEQNHVAENSTPSMASTWLSNILPPAP 594
            ...|:.:|.      |..........||:...:.........|..|.:.|..||          |
  Fly   486 GLPIAENSCDWQLIYGLDCQSYMSDFQPDLRFRFSLGFTALWHRLEGNLPLHAS----------P 540

  Fly   595 TRPDSIENSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKS 652
            .|...::|.      |.. .||:.|:     |..||            ..::|.|:||
  Fly   541 FRIQKLQNG------HKK-CSPLPPL-----VNGNH------------WQMLESLVKS 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_001259946.1	DLP_1	23..301	CDD:206738	55/305 (18%)
		CrfC	88..728	CDD:223771	109/621 (18%)
		Dynamin_M	226..507	CDD:279383	47/309 (15%)
		GED	643..729	CDD:280391	4/10 (40%)
fzo	NP_732840.1	DLP_2	87..334	CDD:206739	61/349 (17%)
		Fzo_mitofusin	572..716	CDD:282633	2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0699
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900