Protein Alignment Drp1 and mx1

DIOPT Version :10

• Sequence 1: NP_608694.2
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: XP_031752404.1
• Gene: mx1 / 101732122
• XenbaseID: XB-GENE-996855
• Length: 647
• Species: Xenopus tropicalis
• Alignment Length: 767
• Identity: 209/767 - (27%)
• Similarity: 334/767 - (43%)
• Gaps: 195/767 - (25%)

  Fly     2 EALIPVINKLQDVFNTVGSD-SIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVL 65
            |.:.|.|: |.|....:|.: .:.||.|.|:|.||||||||:|::.|.: ||||:|||||.||.|
 Frog    33 EKIRPCID-LIDSLRALGVEKDLALPAIAVIGDQSSGKSSVLEALSGVT-LPRGSGIVTRCPLEL 95

  Fly    66 QLIYSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDEIR----KEIENETERA----AGSNK 122
            :|          :.|...|:    |.    .|..:.| .||:    .::|.|.:||    |||.|
 Frog    96 KL----------KKAMKKTT----WS----GKISYRD-HEIKIASAADVEEEVKRAQNLMAGSGK 141

  Fly   123 GICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAAN 187
            ||..|.|:|::.|..|.:|||:||||||:|.:.|||:|||.|||:::.|||:...:|.|.|..:|
 Frog   142 GISDELISLEVISPDVPDLTLIDLPGITRVALPDQPKDIEQQIKKMIRKYIQKQETINLVVVPSN 206

  Fly   188 TDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAG--TDAIDILCGRVIPVKLGIIGVMNRSQKD 250
            .|:||:|||::|::|||:|.|||.::||.||:|.|  ||.|.::...|..:..|.:.|..|.|::
 Frog   207 VDIATTEALEMAREVDPNGERTLGILTKPDLVDRGAETDVISVVRNLVYSLNKGYMIVKCRGQQE 271

  Fly   251 IMDQKHIDDQMKDEAAF----------LQRKYPTLATRNGTPYLAKTLNRLLMHHIRDCLPDLKT 305
            |.:...:.|.:.:|..|          |:..|.|:|...|     |..|.|:.|.:|: ||.|||
 Frog   272 IQENLSLKDALVNEQNFFKEHEHFSVLLEEGYATIACLAG-----KLTNELVAHIVRN-LPTLKT 330

  Fly   306 RVNIMATQFQSLLNSYGEDVSDKSQT-----LLQIITKFSSAYCCTIEGTARNIETTELCGGARM 365
            ::.....:.:..|.:.|..|.| |:|     |:..|.:|:.|.....:|..   |.|.  |..::
 Frog   331 QIRKKLDEAEEKLRNIGSGVPD-SETEKLTFLIDKIRRFNDAITHATQGEE---EMTN--GFLKL 389

  Fly   366 GYIFHETFGRTLDSIHPLA-GLS---KMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEP 426
            ..|....|.....:|...: |..   |.||........|.....||....||.:.::||..||||
 Frog   390 STIMRNYFYSWELTIQETSKGFQNKLKEDITVYENQYRGRELPGFVSFKVFENIARKQIHSLEEP 454

  Fly   427 SLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHE----KIVDVVTQLLR--RRLPHTNVMVENI 485
            :   :|.:.:...::..|......:..|.||.|:.    :|.|:..:.:|  .:...|...:|.:
 Frog   455 A---IEKLKQVTDKVKTHFSQIAMRHFLSFPNLYRCTKVRIEDICCEQMREAEKTIRTQFKMEKM 516

  Fly   486 VAIELAYINTKHPDFHKDAALVPSLLK--TDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQ 548
            :     |...|         |...|||  .|:|
 Frog   517 I-----YCQDK---------LYGVLLKEVRDAD-------------------------------- 535

  Fly   549 PQQQQPPQPNSSQQQYSQVHEQNHVAENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNI 613
                 .|||                                                     |.:
 Frog   536 -----APQP-----------------------------------------------------NKV 542

  Fly   614 V--SPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNY 676
            |  |.:||.              ||..| ...|.:.:.|::||..:.:.:.:.:|..|.:::::.
 Frog   543 VTFSSIKPT--------------LTPME-ISFDEMRYHIQAYFRSLTERLSNQIPIIIQYYVLHE 592

  Fly   677 VKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISE 728
            ..:||||:::..:.:.:..:.||.|.:..:..||...|.::.|:.|:..:::
 Frog   593 FSNNLQSQIMQLIQERENLDALLAEKNDFSRERKNLKDQIERLSAASQRLAK 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_608694.2	DLP_1	23..301	CDD:206738	118/297 (40%)
		Dynamin_M	224..507	CDD:460033	71/307 (23%)
		GED	639..729	CDD:460495	19/90 (21%)
mx1	XP_031752404.1	DLP_1	54..326	CDD:206738	118/297 (40%)
		Dynamin_M	245..532	CDD:460033	75/315 (24%)
		GED	556..645	CDD:460495	19/90 (21%)