Protein Alignment Drp1 and dnm3b

DIOPT Version :10

• Sequence 1: NP_608694.2
• Gene: Drp1 / 33445
• FlyBaseID: FBgn0026479
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: XP_073777964.1
• Gene: dnm3b / 100331916
• ZFINID: ZDB-GENE-140822-1
• Length: 836
• Species: Danio rerio
• Alignment Length: 781
• Identity: 299/781 - (38%)
• Similarity: 441/781 - (56%)
• Gaps: 94/781 - (12%)

  Fly     1 MEALIPVINKLQDVFNTVG-SDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLV 64
            ||.|||::|:|||.|:::| |.::.||||.|:|.||:|||||:|:.|||.|||||:|||||||||
Zfish     6 MEDLIPLVNRLQDAFSSIGQSCNLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLV 70

  Fly    65 LQLIYSPLDDRENRSAENGTSNAEEWGRFLHTK-KCFTDFDEIRKEIENETERAAGSNKGICPEP 128
            ||||               .||. ||..|||.| |.||||||:|:|||.||:|..|:||||.|.|
Zfish    71 LQLI---------------NSNT-EWAEFLHCKGKKFTDFDEVRQEIEAETDRVTGANKGISPVP 119

  Fly   129 INLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATS 193
            |||::||.:|:||||:||||||||||||||.|||.||:|:::::|...:.:|||||.||||:|.|
Zfish   120 INLRVFSPNVLNLTLIDLPGITKVPVGDQPADIEQQIREMIMQFICRESCLILAVTPANTDLANS 184

  Fly   194 EALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHID 258
            :||||||||||.|.||:.|:|||||||.||||.|:|..:::|::.|.|||:|||||||..:|.|.
Zfish   185 DALKLAKDVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDIK 249

  Fly   259 DQMKDEAAFL--QRKYPTLATRNGTPYLAKTLNRLLMHHIRDCLP----DLKTRVNIMATQFQSL 317
            ..:..|..|.  ...|..:|...|||:|.|.||:.|.:||||.||    .|:|::..:..:.:..
Zfish   250 AALAAERKFFLTHPSYRHMADSMGTPHLQKVLNQQLTNHIRDTLPAFRSKLQTQLLALDREAEEY 314

  Fly   318 LNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLDSIHP 382
            .:...:|.|.|::.|||::.:||..:...|||:...::|.||.|||::..||||.|...|..:..
Zfish   315 RHYRPDDPSRKTKALLQMVQQFSVDFEKRIEGSGDQVDTVELSGGAKINRIFHERFPFELVKMEC 379

  Fly   383 LAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGN 447
            .....:.:|..||:|..|.|..||.|:::||.:||:|:.:::||.::|::|:.:|:...|:.|.|
Zfish   380 DEKEMRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQVVKIKEPCIKCIDLVVQELINTVRQCSN 444

  Fly   448 EVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLK 512
            ::..    ||:|.|:...:||..:|.|.......|..::.|:||||||.|.||...|    :..:
Zfish   445 KLDS----FPRLQEETERIVTTHIRDRESQAKEQVLLLIDIQLAYINTNHEDFIGFA----NAQQ 501

  Fly   513 TDSDPYSQINLGQRRANTPR------NHMS---------------PQISSHSAGSQQPQQQQPPQ 556
            ..|....:.:.|.:.....|      |::|               ..:|......::.::...|.
Zfish   502 RSSQANKKSSAGNQELQVIRKGWLTINNISIMKGGAKEYWFVLTAESLSWFKDDEEKEKKYMLPL 566

  Fly   557 PN-----------SSQQQYSQVH-EQNHVAENS--------TPSMASTWLSNILPPAPTRPDSIE 601
            .|           ||:..::..: ||.:|.:::        |.....:|.:::|........:..
Zfish   567 DNLKVRDVEKSFMSSKHMFAIFNTEQRNVFKDNRFLELACDTQEEVDSWRASLLRAGVYPEKAAV 631

  Fly   602 NSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVP 666
            .|.::.|..|..:.|                     :.::..:.|.:|:.||..||.|.|:|.:|
Zfish   632 ESDSSGPAENFSMDP---------------------QLERKVETIRNLVDSYMAIVNKCIRDLMP 675

  Fly   667 KAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISEIRE 731
            |:|||.::|.|||.:.:||:..||.:.....|::||.....||.|......||..|..||.:|..
Zfish   676 KSIMHLMINNVKDFINAELLAQLYSAGDQNALMDESQEQVQRRDEVLRTHTALKEALAIIGDIST 740

  Fly   732 T 732
            |
Zfish   741 T 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drp1	NP_608694.2	DLP_1	23..301	CDD:206738	163/280 (58%)
		Dynamin_M	224..507	CDD:460033	103/288 (36%)
		GED	639..729	CDD:460495	33/89 (37%)
dnm3b	XP_073777964.1	None