DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad1 and Rad1

DIOPT Version :9

Sequence 1:	NP_477440.1	Gene:	Rad1 / 33440	FlyBaseID:	FBgn0026778	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001276376.1	Gene:	Rad1 / 19355	MGIID:	1316678	Length:	280	Species:	Mus musculus

Alignment Length:	279	Identity:	78/279 - (27%)
Similarity:	153/279 - (54%)	Gaps:	19/279 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTDVEPSPYGDCKFVARVEHIKTFIQAIKSICFNDYGMVQVSEDGLRITVEQGKSIQATLFMPPG 65
            :|......|.....||.:::::.....:|:|.|.::.....:::|:::|||..|.:||..|:...
Mouse     4 LTQYNEEEYEQYCLVASLDNVRNLSTVLKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQAD 68

  Fly    66 AFMEFRVQDFQ-CFGVKMNVLSECLSLFGSAD-----CSLRMMYRDKGDPLKIILYPHDDDDVST 124
            .|.||.:|:.. .|.:.:.:|.:|||:|||:.     .:|||.|:..|.||.:.|   ::..|.|
Mouse    69 VFQEFVIQEESVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFL---EEGGVVT 130

  Fly   125 ECAIKTMDCDEPIDYD---QNLKDPDLNVIFVRGPNLSKVFNELEKSAEEFEFVTSPNRPHFKIT 186
            .|.|.|.:.:|.:|:|   .|:    :|.|.::...|.:.|:||:.:.:..:...||::|:|:::
Mouse   131 VCKITTQEPEETLDFDFCSTNV----MNKIILQSEGLREAFSELDMTGDVLQITVSPDKPYFRLS 191

  Fly   187 TVGIMQAVFS-VEVAKTSPMMMMFNCKQTVVARYKSQQIRMTNKAMQSATKVAIKTNSVGLLELH 250
            |.|  .|..| ::..|.|.::..|:|.:|.|.|||...::.:.||:..:.||:|:|::.|.|.|.
Mouse   192 TFG--NAGNSHLDYPKDSDLVEAFHCDKTQVNRYKLSLLKPSTKALALSCKVSIRTDNRGFLSLQ 254

  Fly   251 LVMQGDSQEEIFIQFFIIP 269
            .:::.:..:..|::::..|
Mouse   255 YMIRNEDGQICFVEYYCCP 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad1	NP_477440.1	PCNA	13..272	CDD:238322	76/267 (28%)
Rad1	NP_477440.1	Rad1	13..253	CDD:280331	74/249 (30%)
Rad1	NP_001276376.1	Rad1	17..257	CDD:396631	74/249 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849945
Domainoid	1	1.000	125	1.000	Domainoid score	I5463
eggNOG	1	0.900	-	-		E1_KOG3194
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37695
Inparanoid	1	1.050	135	1.000	Inparanoid score	I4555
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59914
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004120
OrthoInspector	1	1.000	-	-		oto92239
orthoMCL	1	0.900	-	-		OOG6_103936
Panther	1	1.100	-	-	LDO	PTHR10870
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1057
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790