Protein Alignment Cyp309a2 and CYP4F2

DIOPT Version :9

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 128/555 - (23%)
• Similarity: 220/555 - (39%)
• Gaps: 130/555 - (23%)

  Fly    32 MYILASLALILLHLLVLPIYLY--------------LTWHHKYWRKRGLVT-----ARPLT-LLG 76
            :.:|...:.:|.|:|......|              ..|   :|..:|:|.     .|.|| |:.
Human    21 LLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNW---FWGHQGMVNPTEEGMRVLTQLVA 82

  Fly    77 TYPGLLTRKSNLVFDVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQS 141
            |||                          .|..|...|    :.|.|:        .|:.|.::|
Human    83 TYP--------------------------QGFKVWMGP----ISPLLS--------LCHPDIIRS 109

  Fly   142 ---SYLRHAKWDK--YARLNPFW-------ASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQM 194
               :....|..||  |:.|.| |       ::|..|.|.|         ..|..|::.     .:
Human   110 VINASAAIAPKDKFFYSFLEP-WLGDGLLLSAGDKWSRHR---------RMLTPAFHF-----NI 159

  Fly   195 LTEYMTQQVAEKNNILETR--------DLCFRYTAHV-------MADFIWGIDAGTLTRPMEQPN 244
            |..|| :...|..||:..:        ..|.....|:       :...::..|:....:|.|...
Human   160 LKPYM-KIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIA 223

  Fly   245 KVQEMASKWTSYAFYMLTL---FMATIVAPCSRLLLRFRFYPKETD----EFFSNLTKESIELRL 302
            .:.|: |...|...:.:.|   |:..:.....|.....|.....||    |....|..:.::..|
Human   224 AILEL-SALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFL 287

  Fly   303 KAGDSTRT-DYLSHLLQLRDQ--KQATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQ 364
            :|...::| |::..||..:|:  |:.:.:|:...|.|.|.:|:||:.:.|...||:||::|..|:
Human   288 QAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQE 352

  Fly   365 KLRVEILSCMASE--KSLDFEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLD 427
            :.|.|:...:...  |.::::.|:.|.:|...:.|||||...:|..::..|...|  |.:.:.
Human   353 RCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIV--LPDGRV-- 413

  Fly   428 VEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKGI-FLPFSDGPRICMGVPLAML 491
            :..|:..:|..:..||:...:|:||.:.|.|||....:|  |..: |:|||.|||.|:|...||.
Human   414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKE--RSPLAFIPFSAGPRNCIGQTFAMA 476

  Fly   492 TLKSALVHILSNFQVV------RGRDRLIPKGDSG 520
            .:|..|...|..|:|:      |.:..|:.:.:.|
Human   477 EMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	119/498 (24%)
CYP4F2	NP_001073.3	DUF4175	4..>57	CDD:372724	5/35 (14%)
		p450	52..515	CDD:365848	123/524 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920