DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp309a2 and CYP96A12

DIOPT Version :9

Sequence 1:	NP_608689.2	Gene:	Cyp309a2 / 33439	FlyBaseID:	FBgn0041337	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_195661.1	Gene:	CYP96A12 / 830105	AraportID:	AT4G39510	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	121/534 - (22%)
Similarity:	210/534 - (39%)	Gaps:	110/534 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LASLALILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVFDVQKIY--- 96
            :||::|:.:.:.::.::.:   ::.|::|......|...::|..||.|       ..:.:||
plant     1 MASVSLLDVAIAIICLFFF---YYMYFKKPHGQVFRNWPVIGMLPGFL-------MVLHRIYNFG 55

  Fly    97 -DKYKGKHRAV---GVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAK----WDKYA 153
             :..:..|...   |.:......:..:||...|.:|.|||        |:|.:.|.    :|.:.
plant    56 VEALEMSHLTFLFKGPWFAEMDMLFTVDPANIHYILSSNF--------SNYTKGADFKEVFDVFG 112

  Fly   154 RLNPFWASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQ------------QVAEK 206
            .: .|.:..:.|:..|..||           :.:..||.|.|:...|:            |..|:
plant   113 EM-IFSSDSELWKNQRKAAQ-----------FMLNHQGFQKLSLSATRSKLYDGLVPLFNQCCEE 165

  Fly   207 NNILETRDLCFRYTAHVMADFIWGIDAGTLTRPMEQPN----KVQEMASKWTSYAFYMLTLFMAT 267
            ..:::.:.:..|:|.......:.|.|..:|:  :|.|.    |..:...:...|.......|.
plant   166 EKVVDLQQVFQRFTFDTTFFIVTGFDPKSLS--IEMPEVEYAKALDDLGEGIFYRHIKPKFFW-- 226

  Fly   268 IVAPCSRLLLRFRFYPK----ETDEFFSNLTKESI-----ELRLKAGDSTRTDYLSHLLQLRDQK 323
                  :|..||....:    |.|..|..::.:.|     |:|.:..|.........||....:.
plant   227 ------KLQNRFGLGQEKRMTEADATFDRVSAKYILAKREEIRSQGIDHHANGESEDLLTSHIKL 285

  Fly   324 QATHDDLVGHA---------LTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKS 379
            ..|..:|:..:         |...|.|.||:.:||....:.|:|||.|..|:|.||:....|:..
plant   286 DTTKYELLNPSDDKFLRDTILAFNLAGRDTTSSALSWFFWLLSENPQVVTKIRKEIIDKNISKDG 350

  Fly   380 LD-FEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHH 443
            .: .|.|..|.||...:|||:||...:....|....|.|:.....    ||....|:|..:....
plant   351 RNGQENLDKLVYLHAALYESMRLYPPVAFQRKSPIKPDVLPSGHK----VEANSVIIIFLFALGR 411

  Fly   444 DKQYFPEPEA-FKPERF--DNGAYQELMRKGI-------FLPFSDGPRICMGVPLAMLTLKSALV 498
            .:..:.|... |||||:  ::|        |:       ||.|:.|||.|.|..|||..:|:.:|
plant   412 MRAVWGEDATEFKPERWVSESG--------GLRHAPSFKFLSFNAGPRTCPGKQLAMTLMKTVVV 468

  Fly   499 HILSNF--QVVRGR 510
            .||.|:  .|::|:
plant   469 EILQNYDIDVIKGQ 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	116/499 (23%)
CYP96A12	NP_195661.1	CYP86A	66..498	CDD:410687	108/459 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010