Protein Alignment Cyp309a2 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001038763.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 491
• Species: Danio rerio
• Alignment Length: 529
• Identity: 106/529 - (20%)
• Similarity: 206/529 - (38%)
• Gaps: 115/529 - (21%)

  Fly    33 YILASLALILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGL--LTRKSNLVFDVQKI 95
            |:|:::.::   .|...:|::.. |.||....|  ..|...|||..|.:  :|:....:.|:..|
Zfish    12 YLLSAVFVV---FLAYCLYIHQV-HQKYDHIPG--PPRDNFLLGHIPTINRVTKSERHMNDLLLI 70

  Fly    96 Y-DKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDS----LQSSYLRHAKWDKYARL 155
            : :||...:| :..|               |.|:: |..|.:.:    :...||:    |.:...
Zfish    71 WAEKYGPVYR-LNSF---------------HYVII-NVHCPEATKTIMMSPKYLK----DPFIYK 114

  Fly   156 NPFWASGQS--------------WRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEK 206
            ..|...|:.              |.|.|.......|.|.||...:.:.:..:.|.:.:.:....|
Zfish   115 RLFGLFGKRFLGYGLVTATDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSERLMDKLEEMAINK 179

  Fly   207 NNILETRDLCFRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLFMATIVAP 271
            ...: ..||....|..::....:|:|. .|.:..:.|                    |...|...
Zfish   180 TPAV-MHDLVNCVTLDIICKVAFGVDL-NLFKQTDNP--------------------FQQAIEQC 222

  Fly   272 CSRLLLRFR-----FYPK----------------ETDEFFSNLTKESIELRLKAGDSTRTDYLSH 315
            ...::|..|     |:||                :|.|.:....|.::|:    |:....|.|:.
Zfish   223 LQGMVLDLRDPFCKFFPKNWKAIQETKGATVLLRKTGEQWIQNRKTAVEI----GEDVPNDILTQ 283

  Fly   316 LLQLRDQKQAT----HDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMAS 376
            :|:...:::..    |:.::.:.:|..:.|.:|:...|..|:..|..:|.:.::.:.|:...:.:
Zfish   284 ILKTAKEEKVNNTKDHEQMLDNFVTFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDEVLGT 348

  Fly   377 EKSLDFEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQF 441
            ::.:.:|.|....||.||:.|:|||....|...:......||     ..:.:..|::::..:|..
Zfish   349 KRDISYEDLGKFTYLSQVLKETLRLYPTAPGTNRWLHEDMVI-----NGIKIPGGISVIFSSYVA 408

  Fly   442 HHDKQYFPEPEAFKPERFDNGAYQELMRKGIFLPFSDGPRICMGVPLAMLT--------LKSALV 498
            ...:::|.:|..|.||||:..|.:...   .:.|||.|||.|:|...:..|        |.:.|:
Zfish   409 QRLEKHFKDPLKFDPERFNVNAPKPYY---CYYPFSLGPRSCLGQVFSQATPAEGALAQLLTQLL 470

  Fly   499 HILSNFQVV 507
            .:.|:|.:|
Zfish   471 TLCSHFLIV 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	98/492 (20%)
cyp46a1.3	NP_001038763.1	p450	39..452	CDD:278495	93/469 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010