Protein Alignment Cyp309a2 and TBXAS1

DIOPT Version :9

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001159725.2
• Gene: TBXAS1 / 6916
• HGNCID: 11609
• Length: 579
• Species: Homo sapiens
• Alignment Length: 576
• Identity: 137/576 - (23%)
• Similarity: 223/576 - (38%)
• Gaps: 148/576 - (25%)

  Fly    34 ILASLALILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVF-------- 90
            :..:|::.||.||    ..|.|.......|.||...:|...:|          ||.|
Human    16 VTVALSVALLALL----KWYSTSAFSRLEKLGLRHPKPSPFIG----------NLTFFRQGFWES 66

  Fly    91 --DVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSS----------- 142
              :::|:|..      ..|.::.|:..|::.:|::..:|||.||..:.:.:.|.
Human    67 QMELRKLYGP------LCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVL 125

  Fly   143 YLRHAKWDKY--ARLNPFWASGQSWRRL-------RTDAQAG-------ISGSRLRQAYNIW--- 188
            :||..:|::.  |.::.|  |.:....|       |.....|       |..:||.:...|:
Human   126 FLRDKRWEEVRGALMSAF--SPEKLNELGLLIMQERIKGHMGGQQAPQRIPPTRLSKPSGIYVNL 188

  Fly   189 -------------EQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMADFIWGIDAGTLTRPM 240
                         .|...:|..:: ::.||..:..:.:.....||..|:|...:|....:...|
Human   189 HYATLPFCMVPLISQACDLLLAHL-KRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAP- 251

  Fly   241 EQPNKVQEMASKWTSYA----FYMLTLFMATIVAPCSRLLLRFRFYPKETDE---FFSNLTKESI 298
            |.|  ..:...::..:.    ..:|.|...:|:.|.:|:|..     |..||   ||:.|.:..|
Human   252 EDP--FVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPN-----KNRDELNGFFNKLIRNVI 309

  Fly   299 ELR-LKAGDSTRTDYLSHLLQLRDQ-----------------------------------KQATH 327
            .|| .:|.:..|.|:|..:|..|..                                   :..|.
Human   310 ALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTV 374

  Fly   328 DDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSLDFEKL-SSLQYL 391
            |::||.|...::.||:.....|..|.|.||.||..|:||..|:........:.:|..| ..|.||
Human   375 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYL 439

  Fly   392 EQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEV-------GMTIMIPNYQFHHDKQYFP 449
            :.||.|:||:            .|...|.:...:.|.||       |..:.:.....|||.:::|
Human   440 DMVIAETLRM------------YPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWP 492

  Fly   450 EPEAFKPERFDNGAYQELMRKGIFLPFSDGPRICMGVPLAMLTLKSALVHILSNFQ 505
            .||.|.||||...|.|: .|...:|||..|||.|:||.|.:|.:|..|:|:|..|:
Human   493 SPETFNPERFTAEARQQ-HRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	127/540 (24%)
TBXAS1	NP_001159725.2	p450	47..576	CDD:306555	127/541 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920