Protein Alignment Cyp309a2 and CYP4F12

DIOPT Version :9

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_076433.3
• Gene: CYP4F12 / 66002
• HGNCID: 18857
• Length: 524
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 101/438 - (23%)
• Similarity: 180/438 - (41%)
• Gaps: 79/438 - (18%)

  Fly   134 CYKDSLQS----SYLRHAKWDKYARLNPFW-------ASGQSWRRLRTDAQAGISGSRLRQAYNI 187
            |:.|:::|    |.....|.:.:.|....|       :.|..|.|.|.........:.|:....|
Human   102 CHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITI 166

  Fly   188 WEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMAS- 251
            :.:...::.:......:|.::.|:..:.....|...:...|:..|:....||.|....:.|:::
Human   167 FNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSAL 231

  Fly   252 ---------KWTSYAFY-------------MLTLFMATIVAPCSRLLLRFRFYPKE-TDEFFSNL 293
                     :...:.:|             ::..|...::..      |.|..|.: .|:||.:.
Human   232 VEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRE------RRRTLPTQGIDDFFKDK 290

  Fly   294 TKESIELRLKAGDSTRTDYLSHLLQLRDQ--KQATHDDLVGHALTVMLDGYDTSGTALLHALYYL 356
            .|           |...|::..||..:|:  |..:.:|:...|.|.|..|:||:.:.|...||.|
Human   291 AK-----------SKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNL 344

  Fly   357 AENPAVQQKLRVEILSCMASE--KSLDFEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIR 419
            |.:|..|::.|.|:...:...  |.::::.|:.|.:|...:.|||||....|..::.||...|
Human   345 ARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIV-- 407

  Fly   420 LSESKSLDVEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFD--NGAYQELMRKG----IFLPFSD 478
            |.:.:.  :..|:|.:|.....||:...:|:||.:.|.|||  |.       ||    .|:|||.
Human   408 LPDGRV--IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENS-------KGRSPLAFIPFSA 463

  Fly   479 GPRICMGVPLAMLTLKSALVHILSNFQVV------RGRDRLIPKGDSG 520
            |||.|:|...||..:|..|..:|.:|:.:      |.:..||.:.:.|
Human   464 GPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	101/438 (23%)
CYP4F12	NP_076433.3	p450	52..506	CDD:306555	99/431 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920