Protein Alignment Cyp309a2 and Cyp4f14

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_071879.1
• Gene: Cyp4f14 / 64385
• MGIID: 1927669
• Length: 524
• Species: Mus musculus
• Alignment Length: 569
• Identity: 126/569 - (22%)
• Similarity: 221/569 - (38%)
• Gaps: 162/569 - (28%)

  Fly    34 ILASLALILLHLLVLPIYLYLTWHH---------KYWRKR--GLVT-----ARPLT-LLGTYP-G 80
            :|...:.||..:|:.....|..:.|         :.|...  |:||     .:.|| |:|||| |
Mouse    23 LLLGASWILARILIQIYAAYRNYRHLHGFPQPPKRNWLMGHVGMVTPTEQGLKELTRLVGTYPQG 87

  Fly    81 LL----------------------------TRKSNLVFDVQKIY----------DKYKGKHRAVG 107
            .|                            ..|..:.:.:.|.:          ||: .:||.
Mouse    88 FLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKPWLGDGLLVSAGDKW-SRHRR-- 149

  Fly   108 VFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYARLNPFWASGQSWRRLRTDA 172
                      :|.|.....:|....:.:.|   |:.:.|||                |:||.:|.
Mouse   150 ----------MLTPAFHFNILKPYVKIFND---STNIMHAK----------------WQRLISDG 185

  Fly   173 QAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVMADFIWGIDAGTLT 237
            .|.:         :::|.     ...||         |::...|           ::..|:....
Mouse   186 SARL---------DMFEH-----VSLMT---------LDSLQKC-----------VFSFDSNCQE 216

  Fly   238 RPMEQPNKVQEM----ASKWTSYAFYMLTLFMATIVAPCSRLLLRFRFYPKETDEFFSNLTKE-- 296
            :..|....:.|:    |.:......:|..|:..|   |..   :|||.......||...:.:|
Mouse   217 KSSEYIAAILELSALVAKRHQQPLMFMDLLYNLT---PDG---MRFRKACNVVHEFTDAVIRERH 275

  Fly   297 ------SIELRLKAGDSTRT-DYLSHLLQLRDQ--KQATHDDLVGHALTVMLDGYDTSGTALLHA 352
                  .::..||:...::| |::..||..:|:  |:.:.:|:...|.|.|.:|:||:.:.|...
Mouse   276 RTLPDQGLDDFLKSKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWI 340

  Fly   353 LYYLAENPAVQQKLRVEILSCMASE--KSLDFEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLP 415
            ||.||.:|..|::.|.|:...:...  :.::::.|:.|.:|...|.|||||...:...::.||..
Mouse   341 LYNLARHPEYQERCRQEVQELLRGREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQD 405

  Fly   416 TVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKG---IFLPFS 477
              |.|.:.::  :..|:..:|..:..||:...:|:||.:.|.|||    .|.::..   .|:|||
Mouse   406 --ILLPDGRT--IPKGIICLISIFGIHHNPSVWPDPEVYDPFRFD----PENIKDSSPLAFIPFS 462

  Fly   478 DGPRICMGVPLAMLTLKSALVHILSNFQVV------RGRDRLIPKGDSG 520
            .|||.|:|...||..:|.||...|..|:::      |.:..||.:.:.|
Mouse   463 AGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELILRAEGG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	103/446 (23%)
Cyp4f14	NP_071879.1	CYP4F	74..515	CDD:410772	116/518 (22%)