Protein Alignment Cyp309a2 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_006524820.1
• Gene: Cyp4f40 / 631304
• MGIID: 3645508
• Length: 551
• Species: Mus musculus
• Alignment Length: 572
• Identity: 130/572 - (22%)
• Similarity: 209/572 - (36%)
• Gaps: 164/572 - (28%)

  Fly    32 MYILASLALILLHLLVLPIYLYL--------------TWHHKYWRKRG--------------LVT 68
            ::.|..::..|...|.....||.              .|   :|...|              |||
Mouse    48 LFFLVGISWFLARFLTQLYTLYAKCQRLCGFPQPPKKNW---FWGHLGMSPPTEEGMKQVTELVT 109

  Fly    69 ARP---LTLLGTYPGLLT------------------RKSNLVFDVQKIY----------DKYKGK 102
            ..|   :|.||....|:|                  .|.::.:...|.:          ||: .:
Mouse   110 TYPQGFMTWLGPIVPLITLCHPDIIRSVLSASAAVAPKDDIFYSFLKPWLGDGLLVSAGDKW-NR 173

  Fly   103 HRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYA-----RLNPFWASG 162
            ||.            :|.|.....:|....:.:.|   |:.:.||||.:.|     |||.|  ..
Mouse   174 HRR------------MLTPAFHFNILKPYVKIFND---STNIMHAKWLRLASGGSTRLNMF--EN 221

  Fly   163 QSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLT---EYMTQQVAEKNNILETRDLCFRYTAHVM 224
            .|...|.|..:...|.:.     |..|:..|.:.   |..|..|.....:|...||.:|.|...|
Mouse   222 ISLMTLDTLQKCVFSFNS-----NCQEKPSQYIAAILELSTLAVKRNEQLLMHVDLLYRLTPDGM 281

  Fly   225 ADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFY----MLTLFMATIVAPCSRLLLRFRFYPKE 285
                                            .||    ::..|...::....|.||
Mouse   282 --------------------------------RFYKACRLVHDFTDAVIQERRRTLL-------- 306

  Fly   286 TDEFFSNLTKESIELRLKAGDSTRT-DYLSHLLQLRDQ--KQATHDDLVGHALTVMLDGYDTSGT 347
                     |...:..:||...::| |::..||..:|:  |:.:.:|:...|.|.|..|:||:.:
Mouse   307 ---------KHGGDDIIKAKAKSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFRGHDTTAS 362

  Fly   348 ALLHALYYLAENPAVQQKLRVEILSCMASE--KSLDFEKLSSLQYLEQVIYESLRLSSLIPQYTK 410
            .|...||.||.:|..|::.|.|:...:...  |.::::.|:.|.:|...|.|||||...:...::
Mouse   363 GLSWILYNLARHPEHQERCRQEVQELLRDRDPKEIEWDDLAQLPFLTMCIKESLRLHPPVTMVSR 427

  Fly   411 VCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKGI-FL 474
            .||..  |.|.:.:.  :..|:..:|..:..||:...:.:||.:.|.|||....|  .|..: |:
Mouse   428 CCTQD--ISLPDGRI--IPKGVICIINIFGTHHNPTVWRDPEVYDPFRFDPENIQ--ARSPLSFI 486

  Fly   475 PFSDGPRICMGVPLAMLTLKSALVHILSNFQVV------RGRDRLIPKGDSG 520
            |||.|||.|:|...||..:|.||...|..|:::      |.:..||.:.:.|
Mouse   487 PFSAGPRNCIGQTFAMSEMKVALALTLLRFRILPDDKEPRRKPELILRAEGG 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	109/444 (25%)
Cyp4f40	XP_006524820.1	CYP4F	101..542	CDD:410772	122/516 (24%)