Protein Alignment Cyp309a2 and CYP4F11

DIOPT Version :9

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001122404.1
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 122/539 - (22%)
• Similarity: 202/539 - (37%)
• Gaps: 165/539 - (30%)

  Fly    60 YWRKRGLVT-----ARPLT-LLGTYP-GL---------------------LTRKSNLVFDVQKIY 96
            :|..:||||     .:.|| |:.||| |.                     :|..|..|.....|:
Human    60 FWGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIF 124

  Fly    97 -----------------DKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYL 144
                             ||: .:||.            :|.|.....:|....:.:..|:.   :
Human   125 YGFLKPWLGDGLLLSGGDKW-SRHRR------------MLTPAFHFNILKPYMKIFNKSVN---I 173

  Fly   145 RHAKWDKYARLNPFWASGQSWRRLRTDAQAGIS----GSRLRQAYNIWEQGGQMLTEYMT----- 200
            .|.||.:.|      :.|.:    |.|....||    .|..:..::......:..:||:.
Human   174 MHDKWQRLA------SEGSA----RLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILEL 228

  Fly   201 QQVAEKNN---ILETRDLC--------FRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWT 254
            ....||.|   :|.|..|.        ||...|::.||...:              :||.
Human   229 SAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAV--------------IQER----- 274

  Fly   255 SYAFYMLTLFMATIVAPCSRLLLRFRFYPKETDEFFSNLTKESIELRLKAGDSTRTDYLSHLLQL 319
                                   |.....:..|:|..|..|           |...|::..||..
Human   275 -----------------------RCTLPTQGIDDFLKNKAK-----------SKTLDFIDVLLLS 305

  Fly   320 RDQ--KQATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSLDF 382
            :|:  |:.:.:|:...|.|.|.:|:||:.:.|...||:||::|..|::.|.|:...:...:.::.
Human   306 KDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEI 370

  Fly   383 E--KLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDK 445
            |  .|:.|.:|...|.|||||...:|..::.||...|  |.:.:.  :..|:..:|.....|::.
Human   371 EWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFV--LPDGRV--IPKGIVCLINIIGIHYNP 431

  Fly   446 QYFPEPEAFKPERFDNGAYQELMRKG---IFLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVV 507
            ..:|:||.:.|.|||    ||.:::.   .|:|||.|||.|:|...||..:|..|...|.:|:::
Human   432 TVWPDPEVYDPFRFD----QENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRIL 492

  Fly   508 ------RGRDRLIPKGDSG 520
                  |.:..||.:.:.|
Human   493 PTHTEPRRKPELILRAEGG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	117/524 (22%)
CYP4F11	NP_001122404.1	p450	52..506	CDD:365848	120/532 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010