Protein Alignment Cyp309a2 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 510
• Identity: 140/510 - (27%)
• Similarity: 247/510 - (48%)
• Gaps: 62/510 - (12%)

  Fly    32 MYILASLAL----ILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGT----YPGLLTRKSNL 88
            |.::.:|::    :|:..||| .|:|.|:.|..::|.|:...:||.||||    |.|:..
Mouse     1 MELIPNLSIETWVLLVTSLVL-FYIYGTYSHGLFKKLGIPGPKPLPLLGTIFNYYDGMWK----- 59

  Fly    89 VFDVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYA 153
             || :..|.|| ||  ..|.:...||.:.::|||:...|||.  .||.......:.....:.|.|
Mouse    60 -FD-EDCYKKY-GK--IWGFYEGPQPILAIMDPEIIKIVLVK--ECYSVFTNRRFFGPVGFMKKA 117

  Fly   154 RLNPFWASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFR 218
            ..   .:..:.|:||||......:..:|::.:.|..|.|.:|...:.:: .||...:..:|:...
Mouse   118 IT---ISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRRE-EEKGEPISMKDIFGA 178

  Fly   219 YTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLFMATIVAPCSRLLLRFRFYP 283
            |:..|:....:|::..:|..|.:...:..:...|:..:..::|::.:...:.|... :|.|..:|
Mouse   179 YSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYE-MLNFSIFP 242

  Fly   284 KETDEFFSNLTKESIELRLKAGDSTRTDYLSHLLQLRDQK-----QATHD-DLVGHALTVMLDGY 342
            :::..||....|...:.||.:....|.|:|..::..::.|     :|..| ::...|:..:..||
Mouse   243 RDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGGY 307

  Fly   343 DTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSLDFEKLSSLQYLEQVIYESLRLSSLIPQ 407
            |.:.|::...:|.||.:|.||:||:.||...:.::..:.::.|..::||:.|:.|||||
Mouse   308 DATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRL------ 366

  Fly   408 YTKVCTLPTVIRLSESKSLDVEV-------GMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQ 465
                  .|..|||......|||:       |..:|||.|..|.:.:|:|||:.|.||||..
Mouse   367 ------YPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSK---- 421

  Fly   466 ELMRKG-----IFLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVVRGRDRLIP 515
              ..||     |::||.:|||.|:|:..|::::|.|::.:|.||.|....:..||
Mouse   422 --ENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIP 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	128/468 (27%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	128/471 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820