Protein Alignment Cyp309a2 and Cyp4a1

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 130/581 - (22%)
• Similarity: 209/581 - (35%)
• Gaps: 155/581 - (26%)

  Fly    18 TRAKGACSNTKRGNMYILASLALILLHLLVLPIYLYLTW------------------HHKYWRKR 64
            ||..|:.|    |.:.:.:.|.|:||.:..:..||...|                  |.::...:
  Rat     9 TRFTGSIS----GFLQVASVLGLLLLLVKAVQFYLQRQWLLKAFQQFPSPPFHWFFGHKQFQGDK 69

  Fly    65 GLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLV 129
            .|  .:.:|.:..:|....|    .|...|.|                   ::|.||:....:|.
  Rat    70 EL--QQIMTCVENFPSAFPR----WFWGSKAY-------------------LIVYDPDYMKVILG 109

  Fly   130 SNFRCYKDSLQSSYLRHAKWDKYARLNPFWASGQSW---RRLRTDA--------QAGISGSRLRQ 183
            .:    .......|...|.|..|..|   ..:||.|   ||:.|.|        ........:|.
  Rat   110 RS----DPKANGVYRLLAPWIGYGLL---LLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRL 167

  Fly   184 AYNIWEQ-GGQMLTEYMTQQVAEKNNILETRDLC-FRYTAHVMAD-----FIWGIDAGTLTRPME 241
            ..:.||| .||..:..:.|.::...  |:|...| |.:...|..|     :|..|  |.|.
  Rat   168 MLDKWEQLAGQDSSIEIFQHISLMT--LDTVMKCAFSHNGSVQVDGNYKSYIQAI--GNLN---- 224

  Fly   242 QPNKVQEMASKWTSYAFYMLTLFMATIVAPCSRLLLRFRFYPKETDEFFSN-------------- 292
                                .||.:.:         |..|:..:|...||:
  Rat   225 --------------------DLFHSRV---------RNIFHQNDTIYNFSSNGHLFNRACQLAHD 260

  Fly   293 -------LTKESIELRLKAGD------STRTDYLSHLL--QLRDQKQATHDDLVGHALTVMLDGY 342
                   |.|:.::   .||:      ..|.|:|..||  ::.:....:..||.....|.|.:|:
  Rat   261 HTDGVIKLRKDQLQ---NAGELEKVKKKRRLDFLDILLLARMENGDSLSDKDLRAEVDTFMFEGH 322

  Fly   343 DTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSLDFEKLSSLQYLEQVIYESLRLSSLIPQ 407
            ||:.:.:....|.||.:|..||:.|.|:.|.:....|:.::.|..:.|....|.|:|||...:|.
  Rat   323 DTTASGVSWIFYALATHPEHQQRCREEVQSVLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPG 387

  Fly   408 YTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKGI 472
            ..:  .|.|.:...:.:||...:.:|:.|  |..||:.:.:|.||.|.|.||   |.........
  Rat   388 IVR--ELSTSVTFPDGRSLPKGIQVTLSI--YGLHHNPKVWPNPEVFDPSRF---APDSPRHSHS 445

  Fly   473 FLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVVRG-------RDRLIPKGDSGFGVVLQ 526
            |||||.|.|.|:|...||..:|..:...|..|:::..       ..||:.|..:|..:.|:
  Rat   446 FLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLVLKSKNGIYLYLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	109/478 (23%)
Cyp4a1	NP_787031.1	CYP4B-like	71..504	CDD:410771	116/511 (23%)