Protein Alignment Cyp309a2 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 133/523 - (25%)
• Similarity: 238/523 - (45%)
• Gaps: 87/523 - (16%)

  Fly    32 MYILASLAL---ILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGT----YPGLLTRKSNLV 89
            |.::::|:|   :||.::::..|.:.|..|..::|:|:...:||..|||    |.||..
  Rat     1 MDLVSALSLETWLLLAIILVLFYRFGTRTHGIFKKQGIPGPKPLPFLGTVLNYYRGLWK------ 59

  Fly    90 FDVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYK-------------DSLQS 141
            ||:    :.||...:..|:|..:.|...::|.|:...|||.  .|:.             .|...
  Rat    60 FDM----ECYKKCGKIWGLFDGQTPVFAIMDTEMIKSVLVK--ECFSVFTNRRNIGPVGIMSKSI 118

  Fly   142 SYLRHAKWDKY-ARLNPFWASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAE 205
            |..:..:|.:| |.|:|.:.||                 ||::.:.|.|..|.:|.:|:.|:| |
  Rat   119 SVAKDEEWKRYRAFLSPTFTSG-----------------RLKEMFPIIEHYGDILVKYLKQKV-E 165

  Fly   206 KNNILETRDLCFRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLFMATIVA 270
            |...|..:::...|:..|:....:.::..::..|.:   ...|...|:..:.|:. .||::.::.
  Rat   166 KGKPLAMKEVFGAYSMDVITSTSFEVNINSINNPKD---PFVEKVKKFQRFDFFD-PLFLSVVLF 226

  Fly   271 PCSR---LLLRFRFYPKETDEFFSNLTKESIELRLKAGDSTRTDYLSHLLQLRD-------QKQA 325
            |...   .:|....:||::..||........:.||.:....|.|:|..::...:       .|..
  Rat   227 PFLTPIYEMLNICLFPKDSVAFFQKFVYRMKQTRLDSKHKHRVDFLQLMMNAHNNSKDKVSHKAL 291

  Fly   326 THDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSLDFEKLSSLQY 390
            :..::|..|:..:...|:|:.:.|...||.||.:|..|:||:.||...:.::....::.:..::|
  Rat   292 SDIEIVAQAIIFIFASYETTSSTLSFVLYSLATHPDSQKKLQEEIDRALPNKAPPTYDTVMEMEY 356

  Fly   391 LEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLD---VEVGMTIMIPNYQFHHDKQYFPEPE 452
            |:.|:.|:.||..:..:..:||        .:...||   :..|..:|||.|...||.|::||||
  Rat   357 LDMVLNETPRLYPIGYRLERVC--------KKDIKLDGVFIPKGSVVMIPFYTLQHDPQHWPEPE 413

  Fly   453 AFKPERFDNGAYQELMRKG-----IFLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVVRGRDR 512
            .|.||||..      ..||     ::|||.:|||.|:|:..|::.:|.||..:|.||......:.
  Rat   414 EFLPERFSK------ENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLCEET 472

  Fly   513 LIP 515
            .||
  Rat   473 QIP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	111/447 (25%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	111/447 (25%)