Protein Alignment Cyp309a2 and cyp-25A3

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 130/528 - (24%)
• Similarity: 227/528 - (42%)
• Gaps: 83/528 - (15%)

  Fly    38 LALILLHLLVLPIYLYLTWHHKYWRKR---GLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYDKY 99
            |..||:.|:...||:.|....:: |.|   ||....|..|:|....::.||:.|.:|  ..||.|
 Worm     6 LTSILVSLVSFIIYVILARKERF-RLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYD--DSYDWY 67

  Fly   100 KGKHR----AVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYARLNPFWA 160
            ...|:    ..|::...|..|.:.:.|...||.:.||..:.|......:...|. |.:.|...:.
 Worm    68 NKLHKQFGETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKL-KESLLQNTYE 131

  Fly   161 SGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVA--EKNNILETRDLCFR-YTAH 222
            ||  |:..|:......|..:::..:........:..|.:.::.:  :|.:|.:.    |: .|..
 Worm   132 SG--WKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEKASSGQKWDIYDD----FQGLTLD 190

  Fly   223 VMADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFYM-LTLFMATIVAPCSRLLLRFRFYPKET 286
            |:....:.||:..    ....|.|           ||: ...|:..|....|:::.....:|:.:
 Worm   191 VIGKCAFAIDSNC----QRDRNDV-----------FYVNARKFITNIDIRHSKIISTSFLFPELS 240

  Fly   287 DEF-----FSNLTKESIEL---------RLKAGD-STRTDYLSHLLQLRDQKQ--ATHDDLVGHA 334
            ..:     |::|.|..|.|         |.:.|: |...|.|..||...|.|.  .|..:::.:.
 Worm   241 KLWKVLYRFTDLAKAEIPLVEGLADVYERRRGGEGSDSVDLLKLLLNREDDKSKPMTKQEVIENC 305

  Fly   335 LTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEK-SLDFEKLSSLQYLEQVIYES 398
            ...:|.||:|:.||:.:..|.|::.|.|||||..||:.  |.|. .|.::.:.:::||:.|..|:
 Worm   306 FAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIME--AKENGGLTYDSIHNMKYLDYVYKET 368

  Fly   399 LRLSSLIPQYTKVCTLPTVIRLSESKSL-DVEV-------GMTIMIPNYQFHHDKQYFPEPEAFK 455
            ||           | .|.||..|..:.| |:.:       |..::...:..|.:.:.:..||.|.
 Worm   369 LR-----------C-YPPVIHFSNRRCLKDITIRGQFYPKGAIVVCLPHTVHRNPENWDSPEEFH 421

  Fly   456 PERFDNGAYQELMRKGIFLPFSDGPRICMGVPLAMLTLKSALVHILSNFQV--VRGRDRLIPKGD 518
            ||||:|  ::|......::||..|||.|:|:..|.:..|:.:..:|..|::  ..|...|||..:
 Worm   422 PERFEN--WEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELKQFEGEADLIPDCN 484

  Fly   519 SGFGVVLQ 526
               ||:::
 Worm   485 ---GVIMR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	109/460 (24%)
cyp-25A3	NP_001040850.1	CYP3A-like	73..495	CDD:410678	108/458 (24%)