Protein Alignment Cyp309a2 and CYP4F3

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 101/404 - (25%)
• Similarity: 182/404 - (45%)
• Gaps: 46/404 - (11%)

  Fly   150 DK--YARLNPFW-------ASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAE 205
            ||  |:.|.| |       ::|:.|.|.|.........:.|:....|:.:...::........:|
Human   121 DKVFYSFLKP-WLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASE 184

  Fly   206 KNNILETRDLCFRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWT----SYAFYMLTLFMA 266
            .:..|:..:.....|...:...::..|:....:|.|....:.|:::..|    ....|:..|:..
Human   185 GSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYL 249

  Fly   267 TIVAPCSRLLLRFR--------FYPKETDEFFSNLTKESIELRLKAGDSTRT-DYLSHLLQLRDQ 322
            |   |..:   |||        |......|....|..:.::..|:|...::| |::..||..:|:
Human   250 T---PDGQ---RFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDE 308

  Fly   323 --KQATHDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASE--KSLDFE 383
              |:.:.:|:...|.|.|.:|:||:.:.|...||:||::|..|::.|.|:...:...  |.::::
Human   309 DGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWD 373

  Fly   384 KLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYF 448
            .|:.|.:|...|.|||||...:|..::.||...|  |.:.:.  :..|:..:|..:..||:...:
Human   374 DLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIV--LPDGRV--IPKGIICLISVFGTHHNPAVW 434

  Fly   449 PEPEAFKPERFDNGAYQELMRKGI-FLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVV----- 507
            |:||.:.|.|||....:|  |..: |:|||.|||.|:|...||..:|..|...|..|:|:
Human   435 PDPEVYDPFRFDPKNIKE--RSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTE 497

  Fly   508 -RGRDRLIPKGDSG 520
             |.:..|:.:.:.|
Human   498 PRRKPELVLRAEGG 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	101/404 (25%)
CYP4F3	NP_000887.2	CYP4F	74..515	CDD:410772	101/404 (25%)