Protein Alignment Cyp309a2 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_608689.2
• Gene: Cyp309a2 / 33439
• FlyBaseID: FBgn0041337
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 133/548 - (24%)
• Similarity: 219/548 - (39%)
• Gaps: 105/548 - (19%)

  Fly    34 ILASLALILLHLLVLPIYLYLTWHHKYWRKRGLVTARPLTLLGTYPGLLTRKSNLVFDVQKIYDK 98
            :..:|:::||.||    ..|.|......||.|:....|...:|          ||:|..|..::.
  Rat    16 VTVTLSVVLLALL----KWYSTSAFSRLRKLGIRHPEPSPFVG----------NLMFFRQGFWES 66

  Fly    99 Y-KGKHR---AVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDKYARLNPFW 159
            : :.:.|   ..|.::.|:..|::.||::..||||.||..:.:.:.|........|....|.
  Rat    67 HLELRERYGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGLEPKLIADSVLMLR--- 128

  Fly   160 ASGQSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQVAEKNNILETRDLCFRYTAHVM 224
              .:.|..:|....:..|..:|.:...:..|..::|..::....|..:.....|..|. :|.:|:
  Rat   129 --DRRWEEVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAFDIQRCYCC-FTTNVV 190

  Fly   225 ADFIWGIDAGTLTRPMEQP--NKVQEMASKWTSYAFYMLTLFMATIVAPCSRLLLRFRFYPKETD 287
            |...:||:..:...| |.|  ...|.:.:..|......|.|...:|:.|.:|:|..     |..|
  Rat   191 ASVAFGIEVNSQDAP-EDPFVQHCQRVFAFSTPRPLLALILSFPSIMVPLARILPN-----KNRD 249

  Fly   288 E---FFSNLTKESIELRLK-AGDSTRTDYLSHLLQ-------------------------LRDQK 323
            |   ||:.|.:..|.||.| ..:..|.|:|..:|.                         :.|..
  Rat   250 ELNGFFNTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSAECMGDPP 314

  Fly   324 QATH----------DDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEK 378
            |..|          |::.|.|...::.|::.:...|....|.||.:|..|::|..|:...|....
  Rat   315 QRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHP 379

  Fly   379 SLDFEKL-SSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEV-------GMTIM 435
            :.::..| ..|.||:.|:.|:||:            .|...|.:...:.|.||       |..:.
  Rat   380 APEYCNLQEGLPYLDMVVAETLRM------------YPPAFRFTREAAQDCEVLGQHIPAGSVLE 432

  Fly   436 IPNYQFHHDKQYFPEPEAFKPERFDNGAYQELMRKGI-FLPFSDGPRICMGVPLAMLTLKSALVH 499
            |.....|||.:::|.||.|.||||.  |...|.:|.. :|||..|||.|:||.|.:|.:|..|:.
  Rat   433 IAVGALHHDPEHWPNPETFDPERFT--AEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQ 495

  Fly   500 ILSNFQV-----------VRGRDRLIPK 516
            :|..|:.           :..:..|.||
  Rat   496 VLHKFRFEACPETQVPLQLESKSALCPK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp309a2	NP_608689.2	CYP6-like	101..526	CDD:410679	117/480 (24%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	116/476 (24%)